DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15221 and PHO84

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_013583.1	Gene:	PHO84 / 854916	SGDID:	S000004592	Length:	587	Species:	Saccharomyces cerevisiae

Alignment Length:	568	Identity:	124/568 - (21%)
Similarity:	207/568 - (36%)	Gaps:	117/568 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EFANMEGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKC 77
            :||::|...|       |.....|:|...|.|....|.:.|.|:.|:....:|..::|.:..|..
Yeast    35 DFAHIEDPLE-------RRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSY 92

  Fly    78 ----DLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAF----- 133
                ...|..:|. :|..:..:|.|:.....|.|||..||.......|.|..||:|:...
Yeast    93 VYWHGSMPGPSQT-LLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSP 156

  Fly   134 SVN-IWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFA----PAMA 193
            ::| :.:|..:|.:.|..|.|.......:..||..|..|        |.: |..:||    ..::
Yeast   157 AINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWR--------GAI-MGAVFANQAWGQIS 212

  Fly   194 IGILPLRIETIVLG-MHFSS----------------WRVLLLANVSIPLLALVGISALPETPKYL 241
            .||:.|.:.....| :.:::                ||:|:.....:.|..|.....:||:|:|.
Yeast   213 GGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQ 277

  Fly   242 LVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVALE--SGGVSLSDVH----GFLDAVRLV--WH 298
            |......|.....:.........|.|:..:....||  |..|...|.|    .|.|..|..  |.
Yeast   278 LDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFGQWK 342

  Fly   299 QTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSS 363
            ....|...|..|.||::.     .|    |:.:....||..:|....:|
Yeast   343 YGKILLGTAGSWFTLDVA-----FY----GLSLNSAVILQTIGYAGSKN---------------- 382

  Fly   364 EDEASSCSVEVDTSTYQV----MIIIAACFVVIYLIFAYIIDYMGKKNLLMA-WMVLT-MICLVA 422
                      |....|..    :|:|.|..:..|.:..:.:|.:|:|.:.:| :::|| :.|::.
Yeast   383 ----------VYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIG 437

  Fly   423 LHYVEQFALVVIALTVV-MAIGNCGGLVSTIAM--EFYPTHINAMGMCFIMMVGRLGAVVGSNIL 484
            ..|.:.....::||.|: ....|.|...:|..:  |.:||...:.........|::||::....|
Yeast   438 FAYHKLGDHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTAL 502

  Fly   485 GRLLFASCD----------PIFWALLALVVLLCTLGYF----LPEKAR 518
            |.|:..:|.          |....:.||.:|   ||.|    :||..|
Yeast   503 GTLIDHNCARDGKPTNCWLPHVMEIFALFML---LGIFTTLLIPETKR 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	107/499 (21%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	102/484 (21%)
PHO84	NP_013583.1	2A0109	49..554	CDD:129965	119/547 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840