DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15221 and NiaP

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001326466.1	Gene:	NiaP / 820491	AraportID:	AT3G13050	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	135/535 - (25%)
Similarity:	219/535 - (40%)	Gaps:	84/535 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDLQPTLNQQGILASAGFLGV 97
            |.:||:...|.|:|...:|...|:.::...:|:|.:|.:...::.....:..|:.::.|..|.|:
plant     9 TVDEALVAMGFGKFQIYVLAYAGMGWVAEAMEMMLLSFVGPAVQSLWNLSARQESLITSVVFAGM 73

  Fly    98 VLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLC 162
            ::.:::.|.::|..||.........::.|...:||||.|...||:.|.|.|..:.||.. :.|..
plant    74 LIGAYSWGIVSDKHGRRKGFIITAVVTFVAGFLSAFSPNYMWLIILRCLVGLGLGGGPV-LASWY 137

  Fly   163 GEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLLLANVSIP-LL 226
            .||....||...:.:.|.|..:..||..::|..::|.      ||     || .|||..|:| .|
plant   138 LEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPR------LG-----WR-WLLAFSSVPSSL 190

  Fly   227 ALVGISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDP---------------SEYPVKEVAL 276
            .|:......|:|:||::|||..|:|.:|..|...|..:.|               ...|.:...|
plant   191 LLLFYRWTSESPRYLILQGRKAEALAILEKIARMNKTQLPPGVLSSELETELEENKNIPTENTHL 255

  Fly   277 ----ESG-GVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTI 336
                ||| .|::|.:  .|.|.:......:.|.....:..||    :.::::|  ...|.::..:
plant   256 LKAGESGEAVAVSKI--VLKADKEPGFSLLALLSPTLMKRTL----LLWVVFF--GNAFAYYGVV 312

  Fly   337 LDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIID 401
            |......|..|....|..|..|.|              |.:...|.|...|.|..: ||.|.::|
plant   313 LLTTELNNSHNRCYPTEKQLRNSN--------------DVNYRDVFIASFAEFPGL-LISAAMVD 362

  Fly   402 YMGKKNLLMAWMVLT--MICLVALHYVEQFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAM 464
            .:|:| ..||.|:.|  :..|..|.:...|...|:.....:.|.....:|...|.|.|||.:...
plant   363 RLGRK-ASMASMLFTCCIFLLPLLSHQSPFITTVLLFGGRICISAAFTVVYIYAPEIYPTAVRTT 426

  Fly   465 GMCFIMMVGRLGAV------VGSNILGRLLFASCDPIFWALLALVVLL------C-----TLGYF 512
            |:.....|||:|.:      ||       |...|......||..||:|      |     |.|..
plant   427 GVGVGSSVGRIGGILCPLVAVG-------LVHGCHQTIAVLLFEVVILVSGICVCLFPFETSGRD 484

  Fly   513 LPEKARSQQKKPSAT 527
            |.:...:.::.|||:
plant   485 LTDSISASKEPPSAS 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	120/480 (25%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	115/465 (25%)
NiaP	NP_001326466.1	MFS	27..476	CDD:421695	123/492 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010