DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15221 and Svop

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_081081.1	Gene:	Svop / 68666	MGIID:	1915916	Length:	548	Species:	Mus musculus

Alignment Length:	543	Identity:	135/543 - (24%)
Similarity:	229/543 - (42%)	Gaps:	113/543 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 REFANMEGGREENLSEKPRPHTF--EEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQ 74
            :||||            |...||  |:|:...|.|||.:||.::.||.:|...:|:|.:|::..|
Mouse    58 KEFAN------------PTDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQ 110

  Fly    75 MKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFS-VNIW 138
            :.|:.:....|..:|.|..|:|::.||...|.::|.:||.|.|:.::..:....|:|||: |..|
Mouse   111 LHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSW 175

  Fly   139 MLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIET 203
            :| |.|.|.||.|.|....| :|..||....:|.:.:.|:..|..:..:|...:|:.::|
Mouse   176 IL-VLRGLVGFGIGGVPQSV-TLYAEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMP----- 233

  Fly   204 IVLGMHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSE 268
             .||     ||.|||.:.:..||..|....|||:.:|.::.|..::::..|
Mouse   234 -SLG-----WRWLLLLSAAPLLLFAVLCFWLPESARYDVLSGNQEKAIATL-------------- 278

  Fly   269 YPVKEVALESGG--------VSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFL 325
               |.:|.|:|.        :|..:..|          :...||.....|.||       :::|:
Mouse   279 ---KRIATENGAPMPLGKLIISRQEDRG----------KMRDLFTPHFRWTTL-------LLWFI 323

  Fly   326 AQGIFMWFPTILDELGTRNGENTLLCTVL----QGFNINSSSEDEASSCSVE---VDTSTYQVMI 383
                  ||.......|.     .||.|.|    ...:|:|..:...:.||:.   :....|..::
Mouse   324 ------WFSNAFSYYGL-----VLLTTELFQAGDVCSISSRKKAVEAKCSLACEYLSKEDYMDLL 377

  Fly   384 IIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMICLVALHYVEQFALVVI---ALTVVMAIGNC 445
            ..........|:..::||.:|:|..:....::..:|.:.|       .:.|   .||:::.|...
Mouse   378 WTTLSEFPGVLVTLWVIDRLGRKKTMALCFIIFSLCSLLL-------FICIGRNVLTLLLFIARA 435

  Fly   446 ---GGLVSTIAM--EFYPTHINAMGMCFIMMVGRLGAVVGSNILGRLLFASCDPIFWALLALVVL 505
               ||..:....  |.|||...|:|:.....:.|:||::...|...:|.:|    .:..||:...
Mouse   436 FISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESS----VYLTLAVYSG 496

  Fly   506 LCTL----GYFLP--EKARSQQK 522
            .|.|    ..|||  .|.|:.|:
Mouse   497 CCLLAGVASCFLPIETKGRALQE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	115/475 (24%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	108/460 (23%)
Svop	NP_081081.1	2A0119	9..519	CDD:273328	134/541 (25%)
Svop	NP_081081.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	521..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010