Protein Alignment CG15221 and SLC22A23

DIOPT Version :10

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_054212174.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 718
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 103/495 - (20%)
• Similarity: 179/495 - (36%)
• Gaps: 123/495 - (24%)

  Fly    76 KCDLQPTLNQQGILASAG---------FLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVS 131
            || .:|.||...:..:|.         .:|::......|.:||..||...|.:::....:..:..
Human   235 KC-WRPELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTV 298

  Fly   132 AFSVNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGI 196
            |.|||:.|....||..||.::|....:::|..|....|.|.. :|:::.|:.||..|       :
Human   299 ALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFM-ITMVASFVAMAGQF-------L 355

  Fly   197 LPLRIETIVLGMHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANN 261
            :|      .|......|:||....:...||.|:..|..||:.::|:.. :..||.:.|...|...
Human   356 MP------GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMAT-QQFESAKRLILHFTQK 413

  Fly   262 SGRDPSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLA 326
            :..:|.                .|:.|           .:|...:........:|.::.:
Human   414 NRMNPE----------------GDIKG-----------VIPELEKELSRRPKKVCIVKVV----- 446

  Fly   327 QGIFMWFPTILDELGTRN-GENTLLCTV--LQGFNINSSSEDEASSCSVEVD--TSTYQVMIIIA 386
                          |||| .:|.::..|  |.|:.|:...........|:|.  .:.|......|
Human   447 --------------GTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTA 497

  Fly   387 ACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMIC-LVALHYVE-------------QFALVV---- 433
            :..:|..|....::.::|::..|:.:|:||.:. |:.|..:.             |..|.|
Human   498 SIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSD 562

  Fly   434 -------IALTVV--MAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNI------ 483
                   ||.::|  .|....|.|......|..||.|...|:..::.....|.:....|
Human   563 SVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQK 627

  Fly   484 ---LGRLLFASCDPIFWALLALVVLLCTLGYFLPEKARSQ 520
               |..::||.|        .|:.::|.|  .||| :|.|
Human   628 GYFLHHIIFACC--------TLICIICIL--LLPE-SRDQ 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	85/434 (20%)
SLC22A23	XP_054212174.1	MFS_SLC22A23	192..637	CDD:341002	92/463 (20%)