Protein Alignment CG15221 and sv2ca

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001121811.1
• Gene: sv2ca / 562345
• ZFINID: ZDB-GENE-060526-233
• Length: 745
• Species: Danio rerio
• Alignment Length: 632
• Identity: 143/632 - (22%)
• Similarity: 243/632 - (38%)
• Gaps: 144/632 - (22%)

  Fly    12 REFANMEGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMK 76
            ||..|.....||.|:::     :|..|...|.|||.::|....||..|...||:..|..::...:
Zfish   123 RELENERQADEEELAQQ-----YELIIQECGHGRFQWQLFFTLGLALMSDGVEVFVVGFVLPSAE 182

  Fly    77 CDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLI 141
            .|:....:..|.|.|..:||:::.:...|.:||..||...|...:.::...:.:|:|.....:.:
Zfish   183 TDMCVPDSSSGWLGSIVYLGMMVGAFFWGGMADKVGRRQCLLICMSLNGFFAFLSSFVQGYGLFL 247

  Fly   142 VFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPL--RIETI 204
            :.|.:.||.|.|....|||...|......|..|::.|..|..:..|:|.|||..|:|.  :|.|.
Zfish   248 LCRMIAGFGIGGAVPIVFSYFAEVLAREKRGEHLSWLCMFWMIGEIYASAMAWAIIPHYGQITTA 312

  Fly   205 ---VLGMH--------------FSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLE 252
               .:..|              |.||||.::......:.|:|.::.:||:|::.|..|:.||:..
Zfish   313 SSQFINYHHYTSWSFSMGSAYQFHSWRVFVVVCALPCVCAVVALTFMPESPRFYLEVGKHDEAWM 377

  Fly   253 VLRSIFANN---SGRDPSEYPVKEVAL-----------ESGGV-------SLSDVHGFLDAVRLV 296
            :|:.|...|   .|:....:.|..:.:           |||..       ..:::||       :
Zfish   378 ILKQIHDTNMRARGQPEKVFTVNRIKIPKQIDEFVEMHESGNFFSKAIFRIKTELHG-------I 435

  Fly   297 WHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDEL--------GTR-NGE------ 346
            |...:..|.......|:.:..:...:.|...|:.:|||.::..|        |.| |.|
Zfish   436 WLNFLKCFNYPVKESTVKLAIVWLTLSFGYYGLSVWFPDVIKHLQNDEYASKGQRHNNERIEDFT 500

  Fly   347 -----------NTLL-------------------------------------CTVLQG--FN--- 358
                       |:|.                                     ||.::.  :|
Zfish   501 FNFTLENQIHTNSLFINDRFINMKFKSVTFINSTFQSCFFEDVTSVGSFFRNCTFIEAVFYNTDI 565

  Fly   359 ----------INSSSEDEASSCSV--EVDTSTYQVMII-IAACFVVI--YLIFAYIIDYMGKKNL 408
                      |||:.....:.|.:  |.|.|.|.|..: ......|:  .::.|.::|.:|:.::
Zfish   566 DDSKLKNTDVINSTFYHNKTGCQMTFEDDYSAYWVYFVNFLGTLAVLPGNIVSALLMDKIGRLSM 630

  Fly   409 LMAWMVLTMICLVALHY--VEQFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMM 471
            |...|:|:.|....|.:  .|...:.::.|...::|.....| ..:..|.|||.....|..|...
Zfish   631 LGFSMILSGISCFFLWFGTSESMMIGMLCLYNGLSISAWNSL-DVVTTELYPTDRRGTGFGFCNA 694

  Fly   472 VGRLGAVVGSNILGRLL-FASCDPIFWALLALVVLL--CTLGYFLPE 515
            :.:|.||:|:.|.|.|: .....||   |||..||:  ..:|..||:
Zfish   695 LCKLAAVMGNLIFGSLVGITKAIPI---LLASSVLVGGGLVGLRLPD 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	125/576 (22%)
		MFS	51..488	CDD:119392	119/561 (21%)
sv2ca	NP_001121811.1	synapt_SV2	3..745	CDD:130366	143/632 (23%)
		Spt5_N	73..>141	CDD:288770	6/22 (27%)
		MFS	157..>360	CDD:119392	50/202 (25%)
		MFS	588..>711	CDD:119392	30/123 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920