DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15221 and svopa

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_005165254.1	Gene:	svopa / 559162	ZFINID:	ZDB-GENE-060526-336	Length:	549	Species:	Danio rerio

Alignment Length:	545	Identity:	132/545 - (24%)
Similarity:	229/545 - (42%)	Gaps:	85/545 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CDR-EFANMEGGRE--ENLS-----------EKPRPHTF--EEAITLTGVGRFHYKLLLICGLCF 58
            |.| |...:||||.  |::|           ..|...||  |:|:...|.|.|.:||.::.||.:
Zfish    30 CGREEVLQVEGGRTDMESVSLADGAPVPREFANPTDDTFMVEDAVEAIGFGTFQWKLSILTGLSW 94

  Fly    59 MGVMVEIMGVSLIMNQMKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCI 123
            |...:|:|.:|::..|:.|:......:..:|.|..|:|:::||...|.::|.:||.|.|:.::..
Zfish    95 MADAMEMMILSILAPQLHCEWALPSWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLW 159

  Fly   124 SSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIF 188
            :....|:|||:.....::..|.|.||.|.|....| :|..||....||...:.|:..|..:..:|
Zfish   160 TLFYGILSAFAPIYGWILFLRALVGFGIGGAPQSV-TLYAEFLPMRSRATCILLIEIFWALGTVF 223

  Fly   189 APAMAIGILPLRIETIVLGMHFSSWRVLLLANVSIPLLALVGISA-LPETPKYLLVQGRGDESLE 252
            ...:||.::|      .||     || .|||..:|||.....:.. |||:.:|.::.|..:::|.
Zfish   224 EVLLAILVMP------TLG-----WR-WLLALSTIPLFIFAFLCFWLPESARYDVLTGNQEKALN 276

  Fly   253 VLRSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICC 317
            .|:.|.|.|:...|....:  ||.:.....:.|                 ||.....|.|:.:..
Zfish   277 TLKRIAAENNVPMPLGKLI--VARQEDRGKIQD-----------------LFSPHFRWTTVLLWF 322

  Fly   318 IQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVE---VDTSTY 379
            |.|...|...|:.:....:..|.|...|..            .|..|   ..||:|   :::..|
Zfish   323 IWFSNAFSYYGVVLLTTELFQEGGVCGGAK------------GSKME---PGCSLECKYLNSDDY 372

  Fly   380 QVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMICLVALHYVEQFALVVIALTVVMAIGN 444
            :.::..........|:..:.||.:|::..:.....:..:|:|.|:    ..:...:|||.:.|..
Zfish   373 KDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCFFVFSLCIVPLY----SCVGRTSLTVFIFIAR 433

  Fly   445 ---CGGLVSTIAM--EFYPTHINAMGMCFIMMVGRLGAVVGSNILGRLLFAS---------CDPI 495
               .||..:....  |.|||...|:|:.....:.|:||::...:...:|.:|         |..:
Zfish   434 AFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQVMLESSVYLTLSVYCCCCL 498

  Fly   496 FWALLALVVLLCTLGYFLPEKARSQ 520
            ..|:.:..:.:.|.|..|.|.:..:
Zfish   499 LAAIASCALPIETTGRGLQESSHRE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	111/460 (24%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	105/445 (24%)
svopa	XP_005165254.1	2A0115	82..482	CDD:273327	108/450 (24%)
svopa	XP_005165254.1	MFS	88..508	CDD:119392	109/470 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010