DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15221 and Svopl

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_008761085.2	Gene:	Svopl / 500085	RGDID:	1566053	Length:	446	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	121/498 - (24%)
Similarity:	203/498 - (40%)	Gaps:	85/498 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GLCFMGVM-----VEIMGVSLIMNQMKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRA 114
            |.||:.::     :|||.::::...::|:.|....|...:.:..|.|.::||...|.|||.:||.
  Rat     2 GFCFLLLLQVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRW 66

  Fly   115 TTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISG-GQACVFSLCGEFHGTGSRIRHVTLL 178
            ..|..:....:..|::::||.:....:..|.:.|..:|| .|..:...  ||..|..|...:.|.
  Rat    67 KILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIKT--EFLPTKYRGYMLPLS 129

  Fly   179 SGFLCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLLLANVSIP-LLALVGISALPETPKYLL 242
            ..|.....:...:||..::|    ||       .|| .|:...||| ::.::....:||:.::.:
  Rat   130 QVFWLAGSLLIISMASVVIP----TI-------GWR-WLIRIASIPGIILIMAFKFIPESARFNV 182

  Fly   243 VQGRGDESLEVLRSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRA 307
            ..|....:|:.|.||...|....| |..:.|..||..|       .|.|.:...:.:|
  Rat   183 STGNTQAALDTLESIAKMNRSVMP-EGRLVEPILEKRG-------RFADLLESKYLRT------- 232

  Fly   308 RLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDE------ 366
                ||.|..|...|.|...|:.:....:|        |..|:|        .|.||.|
  Rat   233 ----TLQIWIIWLGISFAYYGVILASAELL--------ERDLVC--------GSKSESEPEVVEN 277

  Fly   367 -------ASSCSVEV-DTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMICLVAL 423
                   .|.|...: ..|.|:.|||.....:.:..:....|:::|::..|...|..|.:..:.|
  Rat   278 MGDAEEGRSPCYCHMFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLL 342

  Fly   424 HYVEQFALVVIALTVVMAIGNCGGLVSTI---AMEFYPTHINAMGMCFIMMVGRLGAVVGSNILG 485
            :.....|.::..|.::.|:  .....:||   ..|.|||.:.|:||.....:.|:||:|...|..
  Rat   343 NICTSSAGLIGFLFMLRAL--VAANFNTIYIYTAEVYPTPMRALGMGTSGSLCRIGAMVAPFISQ 405

  Fly   486 RLLFASCDPIFWALLAL---VVLLCTLGYF-LP--EKARSQQK 522
            .|:.||    |...|.|   |.::|.:..| ||  .|.|:.|:
  Rat   406 VLMSAS----FLGALCLFSSVCVVCAISAFTLPIETKGRALQQ 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	107/456 (23%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	107/456 (23%)
Svopl	XP_008761085.2	MFS_SVOPL	3..434	CDD:341000	115/485 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346935
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940