DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15221 and T22F7.1

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_497209.1	Gene:	T22F7.1 / 3564822	WormBaseID:	WBGene00020701	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	567	Identity:	104/567 - (18%)
Similarity:	187/567 - (32%)	Gaps:	193/567 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVS------------- 69
            |||::...|       .||.:..|...| .|.|.:||.:.|:..:..:..:|
Worm    50 EGGQDVISS-------VEELLKATTAWR-PYPLFIICSMSFLWSLCALSAISPAFTAPAGDECTE 106

  Fly    70 -----LIMNQMKCDLQPTLNQQG-ILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCS 128
                 .|.|:.....:..|.:.. :..|..|||.:|.......:||.:||...:...|.::.:..
Worm   107 NCSFYTIQNEFNLTSKFFLVEPAELTTSIYFLGNLLIGQLFAVVADRFGRRPIIIICLLLTGIVG 171

  Fly   129 IVSAFSVNIWMLIVFRFLTGF---------FISGGQACVF---SLCGEFHGTGSRIRHVTLLSGF 181
            .:.:.:.|..:|:|.||:.|.         ::..|::...   ||...|.|.           .:
Worm   172 SLGSLAPNFPLLLVARFIQGSCYTPLTTVNYVLSGESIPHRSQSLTSIFFGV-----------SW 225

  Fly   182 LCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLLLANVSIP--LLALVGISALPETPKYLLVQ 244
            :|.....||               |.:.|::||.|.|| .::|  |:|:..:..|||:..|.:.:
Worm   226 VCGYCFLAP---------------LSVWFNTWRSLQLA-TALPNILVAVFLMGTLPESVGYSIEK 274

  Fly   245 GRG----------------------DESLEVLRSIFANNSGRDPSEYPVKEVALESGGVSLSD-- 285
            ...                      |..:|....|..::|....:...:.|:..|    .|||
Worm   275 KNRKAVQKWIKRNELLSCKKLNYDLDMIMEKTEKIATSSSPTPQNRLTIFEMIRE----ILSDRE 335

  Fly   286 ------VHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGI-----FMWFPTILDE 339
                  |..||      |..|...:....|..| ::.....::.||..|:     :::.|..|..
Worm   336 ITRRIIVETFL------WILTFMTYCALSLTST-SVGNSDPLVSFLFSGVVELPAYLFIPICLTR 393

  Fly   340 LGTRNGENTLLC------TVLQGFNINSSSEDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAY 398
              |:......||      .:|..:.:::             |||.:.::.::|........||.:
Worm   394 --TKRRPTRFLCHFTGSMALLTMYFLSN-------------DTSLHLIIWLVAKFCASCCYIFCF 443

  Fly   399 IIDYMGKKNLLMAWMVLTMICLVALHYVEQFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINA 463
            |                                                    .|.|.:||...:
Worm   444 I----------------------------------------------------YAAELFPTWCRS 456

  Fly   464 --MGMCFIMMVGRLGAVVGSNILGRLLFASCDPIFWALLALVVLLCT 508
              :|:|....  .:||:|..:|.  |:.::.....:.:||.|.|||:
Worm   457 CCIGVCSTCC--NIGAIVAPHIF--LIDSAAPGAQFLVLAAVGLLCS 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	92/527 (17%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	87/512 (17%)
T22F7.1	NP_497209.1	MFS_SLC22	101..505	CDD:340875	90/508 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162954
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930