DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15221 and Slc22a5

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_062142.1	Gene:	Slc22a5 / 29726	RGDID:	3702	Length:	557	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	103/461 - (22%)
Similarity:	163/461 - (35%)	Gaps:	126/461 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 ILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFIS 152
            :..|..|:||::.|...|.|:|.:||...|...:.:.:..|.:..||||..|..|...|.|....
  Rat   144 LTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQI 208

  Fly   153 GGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLL 217
            ......|.|..|......||...||   .:|:...|    ...:|||      .......||:||
  Rat   209 SNYVAAFVLGTEILSKSIRIIFATL---GVCIFYAF----GFMVLPL------FAYFIRDWRMLL 260

  Fly   218 LANVSIPLLALVGISA------LPETPKYLLVQGRGDESLEVLR------SIFANNSGRDPSEYP 270
            ||      |.:.|:..      :||:|::|:.|||..|:..::|      .|.|.::..||||
  Rat   261 LA------LTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSE-- 317

  Fly   271 VKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPT 335
                 |:.........|...|.||                 |.||..|..:      .|.:|.
  Rat   318 -----LQDLNSKKPQSHHIYDLVR-----------------TRNIRIITIM------SIILWL-- 352

  Fly   336 ILDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEVDT-----STYQVMIIIAACFVVIYLI 395
                            |:..|:            ..:.:||     ..|....::||..|..|::
  Rat   353 ----------------TISVGY------------FGLSLDTPNLHGDIYVNCFLLAAVEVPAYVL 389

  Fly   396 FAYIIDYMGKKNLLMAWMVL--TMICLVALHYVEQFALVVIALTVVMAIGNCG-----GLVSTIA 453
            ...::.::.::..:.|.:.|  :::..:.|...|.|.|    .|.::.:|..|     .:|....
  Rat   390 AWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSELFYL----STALVMVGKFGITSAYSMVYVYT 450

  Fly   454 MEFYPTHINAMGMCFIMMVGRLGAVVG---------SNILGRLLFASCDPIFWALLALVVLLCTL 509
            .|.|||.:..||:.......|||:::.         ...|..:|..|          |.:|...|
  Rat   451 AELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGS----------LTILTAIL 505

  Fly   510 GYFLPE 515
            ..|.||
  Rat   506 TLFFPE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	95/432 (22%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	95/432 (22%)
Slc22a5	NP_062142.1	2A0119	12..520	CDD:273328	103/461 (22%)
		MFS	123..510	CDD:119392	101/458 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	537..557
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840