DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15221 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	575	Identity:	123/575 - (21%)
Similarity:	198/575 - (34%)	Gaps:	174/575 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LTGVGRFHY----KLLLICGLCFMGVMVE---------------------------IMGVSLIMN 73
            |.|||||..    .|||.|||......::                           .:..::.:|
  Rat    10 LGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEATTNDSGAWLRATIPLN 74

  Fly    74 Q----MKCD---------LQPTLNQQGI-----------------------------------LA 90
            |    ..|.         |:|..:..|:                                   ||
  Rat    75 QHGVPEPCQRYTEPQWALLEPNTSSHGVATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLA 139

  Fly    91 SAGFL-GVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGG 154
            .:.:: ||::.:...|.|||..||...|.::....:|...|:|:..:.....:||||.|...||.
  Rat   140 QSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGSFSAYCIFRFLMGMTFSGI 204

  Fly   155 QACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHFSSWRVLLLA 219
            .....||..|:..|..|.....||.....:..:....:|..|.|              ||.|..|
  Rat   205 ILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRP--------------WRWLQFA 255

  Fly   220 NVSIPLLALVGIS-ALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVA---LESGG 280
             ||.|.|.....| .|||:.::||:.|:..::::.||.:...|..:...|....||.   :::..
  Rat   256 -VSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTIEVVSSYIQNEF 319

  Fly   281 VSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNG 345
            .|:...:..||..|....:.|             .||:..:          ||...:...|
  Rat   320 ASVRTSNSILDLFRTPGIRKV-------------TCCLMMV----------WFSNSVAYYG---- 357

  Fly   346 ENTLLCTVLQGFNINSSSEDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLM 410
                |...||.|.:                 |.|.|..:.....:...|:....:.|:|::..:.
  Rat   358 ----LAMDLQKFGL-----------------SIYLVQALFGIIDIPAMLVATTTMIYVGRRATVS 401

  Fly   411 AWMVLTMICLVALHYVEQFALVVIALTVVMAIGNCGGLVSTIAM------EFYPTHINAMGMCFI 469
            :::||..:.::|..:|.:....:  .||..|:|. |.|.|:...      |.|||.|..|||.|.
  Rat   402 SFLVLAGLMVIANMFVPEDLQTL--RTVQAALGK-GCLASSFICVYLFTGELYPTEIRQMGMGFA 463

  Fly   470 MMVGRLGAVVGSNI--LGRLLFASCDPIF-------WALLALVVLLCTLGYFLPE 515
            .:..|||.:....|  ||.:     .|:.       .::||.:.::|    ||.|
  Rat   464 SVNARLGGLAAPLITTLGEI-----SPVLPPVSFGATSVLAGMAVIC----FLTE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	116/539 (22%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	109/524 (21%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	103/479 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840