Protein Alignment CG15221 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 495
• Identity: 118/495 - (23%)
• Similarity: 206/495 - (41%)
• Gaps: 114/495 - (23%)

  Fly    57 CFMGVMVEIMGVSLIMN-QMKC------DLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRA 114
            |..|.:.:..|.|::.. .:.|      ||..:|...|.     |:|.|    .:|:|||.:||.
Mouse   122 CEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGF-----FIGAV----GIGYLADRFGRK 177

  Fly   115 TTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLS 179
            ..|...:.|:::..::.|.|.|...::|||||.|.....|....:.|..||.|.|.|
Mouse   178 FCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYR-------- 234

  Fly   180 GFLCMAMIFAPAMAIGILPLRIETIVLGMHFS--SWRVLLLANVSIP-LLALVGISALPETPKYL 241
              ..:.:.:..|..:|:|      |:.|:.::  :||.|..| |::| ...|:....:||:|::|
Mouse   235 --RTVGICYQIAFTVGLL------ILAGVAYALPNWRWLQFA-VTLPNFCFLLYFWCIPESPRWL 290

  Fly   242 LVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVAL---ESGGVSLSDVHGFLDAVRL--VWHQTV 301
            :.|.:..:::::::.| |..:|:   ..||...:|   |..|:.|:.  .|||.||.  :...|:
Mouse   291 ISQNKNAKAMKIIKHI-AKKNGK---SVPVSLQSLTADEDTGMKLNP--SFLDLVRTPQIRKHTL 349

  Fly   302 PLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDE 366
            .|.|.   |.|.::         |.||:.|       .:|.. |:|..|
Mouse   350 ILMYN---WFTSSV---------LYQGLIM-------HMGLA-GDNIYL---------------- 378

  Fly   367 ASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMI----CLVALHYVE 427
                     ...|..::...|.|::|     ..||.:|::   ..|.|..|:    ||.::...:
Mouse   379 ---------DFFYSALVEFPAAFIII-----LTIDRIGRR---YPWAVSNMVAGAACLASVFIPD 426

  Fly   428 --QFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRL--L 488
              |:..:.:|....|.|.....:|..:..|.|||:|..:.:.....:..:|.:|...::.||  :
Mouse   427 DLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDI 491

  Fly   489 FASCDPIFWALLALV----VLLC--TLGYFLPEKARSQQK 522
            :.....:.:|::.||    |||.  |.|..|||.....:|
Mouse   492 WLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	95/407 (23%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	116/487 (24%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		2/3 (67%)