Protein Alignment CG15221 and SVOPL

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001132928.1
• Gene: SVOPL / 136306
• HGNCID: 27034
• Length: 492
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 128/530 - (24%)
• Similarity: 219/530 - (41%)
• Gaps: 86/530 - (16%)

  Fly    20 GREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDLQPTLN 84
            |..|...::|:..|.|:|:...|.||||..|.||.|...:...:|||.::::...::|:.|....
Human    20 GTAEPQVKEPKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENW 84

  Fly    85 QQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGF 149
            |..::.:..|.|.::.|...|.|||.:||...|..:....:..|::::|:.:....:..|.:.|.
Human    85 QVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGC 149

  Fly   150 FISG-GQACVFS---LCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHF 210
            .:|| .|..:..   |..::.|....:..|..|:|.|         :.||:..:.|.||
Human   150 GVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSL---------LIIGLASVIIPTI------ 199

  Fly   211 SSWRVLLLANVSIP-LLALVGISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVKEV 274
             .||.|:.. .||| ::.:|....:||:.::.:..|....:|..|..:...|....| |..:.|.
Human   200 -GWRWLIRV-ASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMP-EGKLVEP 261

  Fly   275 ALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDE 339
            .||..|       .|.|.:...:.:|           ||.|..|...|.|...|:.:....:|
Human   262 VLEKRG-------RFADLLDAKYLRT-----------TLQIWVIWLGISFAYYGVILASAELL-- 306

  Fly   340 LGTRNGENTLLC-------TVLQGFNINSSSEDEASSCSVEV-DTSTYQVMIIIAACFVVIYLIF 396
                  |..|:|       .|:.|    ..|.:..|.|...: ..|.|:.|||.....:.:..:.
Human   307 ------ERDLVCGSKSDSAVVVTG----GDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLN 361

  Fly   397 AYIIDYMGKKNLLMAWMVLTMICLVALHYVEQFALVVIALTVVMAIGNCG-GLVSTIAMEFYPTH 460
            ...|:::|::..|...|..|.:..:.|:.....|.::..|.::.|:.... ..|.....|.|||.
Human   362 ILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTT 426

  Fly   461 INAMGMCFIMMVGRLGAVV---------GSNILGRL-LFASCDPIFWALLALVVLLCTLGYF-LP 514
            :.|:||.....:.|:||:|         .::|||.| ||:|           |.::|.:..| ||
Human   427 MRALGMGTSGSLCRIGAMVAPFISQVLMSASILGALCLFSS-----------VCVVCAISAFTLP 480

  Fly   515 --EKARSQQK 522
              .|.|:.|:
Human   481 IETKGRALQQ 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	112/475 (24%)
		MFS	51..488	CDD:119392	105/460 (23%)
SVOPL	NP_001132928.1	2A0115	34..454	CDD:273327	109/467 (23%)
		MFS	51..480	CDD:119392	111/487 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153344
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940