Protein Alignment CG15221 and Sv2b

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_476555.1
• Gene: Sv2b / 117556
• RGDID: 619716
• Length: 683
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 128/613 - (20%)
• Similarity: 230/613 - (37%)
• Gaps: 149/613 - (24%)

  Fly    15 ANMEGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDL 79
            |::...|.|:  |:...|.:|..|...|.|||.:.|..:..|..|...||:..||..:...:.|:
  Rat    78 ADLMAERMED--EEQLAHQYETIIDECGHGRFQWTLFFVLVLALMADGVEVFVVSFALPSAEKDM 140

  Fly    80 QPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFR 144
            ..:.:::|:|....:||::..:..:|.|||..||...|..:|.|::..:.:|:|.......:..|
  Rat   141 CLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCR 205

  Fly   145 FLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLG-- 207
            .::|..|.|....||:...||.....|..|::.|..|.....|:|.|||..|:|.......:|
  Rat   206 LISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTN 270

  Fly   208 MHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANN---SGRDPSEY 269
            .||.||||.::.......:::|.:..:||:|::||..|:.||:..:|:.:...|   .|.....:
  Rat   271 YHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVF 335

  Fly   270 PVKEVALESGGVSLSDVHG------------FLDAVRLVWHQTVPLFYRARLWHTLNICCIQFII 322
            .|..:..........::..            |:...:.||...:.........:||.:..:.|.:
  Rat   336 TVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTM 400

  Fly   323 YFLAQGIFMWFPTIL----DE-----LGTRNGENTLLCTVLQGFNINSSSEDEA----------- 367
            .....|:.:|||.::    ||     :....||:      :.|..||.:.|::.
  Rat   401 ALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEH------VHGATINFTMENQIHQHGKLVNDKF 459

  Fly   368 ------------------------------SSCSVE----VDTSTYQVMII----IAACFV---- 390
                                          .:|::|    .:|..|:...|    |.:.|:
  Rat   460 IKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFIDCRFINSTFLEQKE 524

  Fly   391 ------------VIYL--------------IFAYIIDYMGKKNLLMAWMVLTMICLVALHYVEQF 429
                        :|||              |.|.::|.:|:..::...|:::.:|...|.:
  Rat   525 GCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFF---- 585

  Fly   430 ALVVIALTVVMAIGN------------CG------GLVSTIAMEFYPTHINAMGMCFIMMVGRLG 476
                         ||            ||      ..:..|.:|.|||:..|.....:..:.:||
  Rat   586 -------------GNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKLG 637

  Fly   477 AVVGSNILGRLL-FASCDPIFWALLALV 503
            |::|:.|....: .....||..|..:||
  Rat   638 AILGNTIFASFVGITKVVPILLAAASLV 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	117/574 (20%)
		MFS	51..488	CDD:119392	111/559 (20%)
Sv2b	NP_476555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..72
		synapt_SV2	8..683	CDD:130366	128/613 (21%)
		MFS	112..>305	CDD:119392	52/192 (27%)
		MFS	534..>675	CDD:119392	30/149 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920