Protein Alignment CG15221 and SLC22A12

DIOPT Version :10

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 118/498 - (23%)
• Similarity: 189/498 - (37%)
• Gaps: 117/498 - (23%)

  Fly    77 CD---LQPTLNQQGILASAGFL-GVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNI 137
            ||   |:|       :|.:.:| |:::.:.|.|..:|.:||...|.::....:|....:||:...
Human   139 CDSHALKP-------MAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAF 196

  Fly   138 WMLIVFRFLTGFFISG--------GQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAI 194
            .:..:||||..|.::|        .::..:...|..| .|||...:.||:     .|.:..|.|
Human   197 PVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLH-AGSRAEPLGLLA-----VMEWTAARA- 254

  Fly   195 GILPLRIETIVLGMHFS------------SWRVLLLANVSIP-LLALVGISALPETPKYLLVQGR 246
              .||.:....||..|.            .|.:|.|. ||:| .|..:....|.|:.::||..||
Human   255 --RPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLV-VSVPFFLCFLYSWWLAESARWLLTTGR 316

  Fly   247 GDESLEVLRSIFANNSGRDPSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWH 311
            .|..|:.|..:.|.|......:....||.|.:....||  .|...|......:...|.:|.
Human   317 LDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELS--MGQPPASLGTLLRMPGLRFRT---- 375

  Fly   312 TLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEVDT 376
                 ||..:.:| |.| |.:|...||               ||....|
Human   376 -----CISTLCWF-AFG-FTFFGLALD---------------LQALGSN---------------- 402

  Fly   377 STYQVMIIIAACFVVIYLIFA-----YIIDYMGKKNLLMAWMVLTMICLVALHYVE------QFA 430
                  |.:...|:.:..|.|     .::.::|::..|.|.::|..:|::|...|.      :.|
Human   403 ------IFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSA 461

  Fly   431 LVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGS--NILG------RL 487
            |.|:.|..|.|...|   ::..:.|.:||.:....:....|..|.||::|.  .:||      .|
Human   462 LAVLGLGGVGAAFTC---ITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPL 523

  Fly   488 LFASCDPIFWALLALVVLLCTLGYFLPEKARSQQKKPSATAKA 530
            |.....|:...|.|| :|..|....||:..:..|.:  |..||
Human   524 LVYGTVPVLSGLAAL-LLPETQSLPLPDTIQDVQNQ--AVKKA 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	97/426 (23%)
SLC22A12	XP_006718493.1	MFS_OAT	109..541	CDD:340932	110/472 (23%)