Protein Alignment CG15221 and sv2b

DIOPT Version :9

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 127/615 - (20%)
• Similarity: 231/615 - (37%)
• Gaps: 170/615 - (27%)

  Fly    22 EENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDLQPTLNQQ 86
            ||.|:     :.:|..|...|.|||.:.|.::.||..|...||:..|..::...:.|:..:.:.:
 Frog   116 EEQLA-----YQYENIIQECGHGRFQWTLFVVLGLALMADGVEVFVVGFVLPSAEKDMCLSRSNK 175

  Fly    87 GILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFI 151
            |:|....:||::|.:...|.|||..||...|..:|.|::..|.||:|.....:.:..|.::||.|
 Frog   176 GMLGLIVYLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFCRLISGFGI 240

  Fly   152 SGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLG--MHFSSWR 214
            .|....||:...||.....|..|::.|..|..:..::|.|||..|:|.......:|  .||.|||
 Frog   241 GGSLPIVFAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHFHSWR 305

  Fly   215 VLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANN---SGRDPSEYPVKEVAL 276
            |.::..|...:.:::.:..:||:|::||..|:.||:..:|::|...|   .|.....:.|..:..
 Frog   306 VFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGEPEKVFTVSHIKT 370

  Fly   277 ESGGVSLSDVHG------------FLDAVRLVWHQTVPLF---------YRARLWHTLNICCIQF 320
            ........::..            .:..::.:|...:..|         :.|.:|.|:::.
 Frog   371 PKQPDEFIEIQSSTGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAVVWFTMSLS---- 431

  Fly   321 IIYFLAQGIFMWFPTILDELGTRN---------GENTLLCTVLQGFNINSSSEDEA--------- 367
              |:   |:.:|||..:..|...:         .||      ::.||.|.:.|::.
 Frog   432 --YY---GLTVWFPDTIRYLQDEDYASKVKRFTDEN------VKNFNFNFTLENQIHEDGEYYND 485

  Fly   368 --------------------------------SSCSVE----VDTSTYQVMIIIA---------- 386
                                            .:|:::    .:|..||...|..
 Frog   486 RFYKMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQP 550

  Fly   387 --ACFV--------VIYL--------------IFAYIIDYMGKKNLLMAWMVLTMICLVALHYVE 427
              .|.:        :|||              |.|.::|.:|:..::...|:::.:|...|.:
 Frog   551 KEGCHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFLFF-- 613

  Fly   428 QFALVVIALTVVMAIGN------------CG------GLVSTIAMEFYPTHINAMGMCFIMMVGR 474
                           ||            ||      ..:..:.:|.|||:..|.....:..:.:
 Frog   614 ---------------GNSESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRATAFGILNGLCK 663

  Fly   475 LGAVVGSNILGRLL-FASCDPIFWALLALV 503
            |.|:.|::|....: .....||..|..|||
 Frog   664 LAAIFGNSIFASFVGITKVIPILLASTALV 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	117/583 (20%)
		MFS	51..488	CDD:119392	111/568 (20%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	127/615 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920