Protein Alignment CG15221 and sv2c

DIOPT Version :10

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_002934873.1
• Gene: sv2c / 100490137
• XenbaseID: XB-GENE-960877
• Length: 725
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 138/620 - (22%)
• Similarity: 249/620 - (40%)
• Gaps: 127/620 - (20%)

  Fly    12 REFANMEGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMK 76
            ||........||.|:::     :|..|...|.|||.:.|..:.|:..|...||:..|..::...:
 Frog   119 RELETERKADEEELAQQ-----YELIIQECGHGRFQWTLFFVLGMALMADGVEVFVVGFVLPSAE 178

  Fly    77 CDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLI 141
            .|:....:..|.|.|..:||:::.:...|.|||..||..:|...:.::...:.:|:|.....:.:
 Frog   179 TDMCIPDSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGLFL 243

  Fly   142 VFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVL 206
            |.|.|:||.|.|.....||...|......|..|::.|..|..:..|:|.|||..|:|....:..:
 Frog   244 VCRLLSGFGIGGALPTAFSYFSEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSM 308

  Fly   207 G--MHFSSWRVLLLANVSIPLL-ALVGISALPETPKYLLVQGRGDESLEVLRSIFANN---SGRD 265
            |  ..|.||||.::. .::|.: |:|.::.:||:|::||..|:.||:..:|:.|...|   .|..
 Frog   309 GSAYQFHSWRVFVIV-CALPCVSAVVALTFMPESPRFLLETGKHDEAWMILKQIHDTNMRARGEP 372

  Fly   266 PSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRAR-----LW-------------HT 312
            ...:.|:.:........|.::    ::....|::.  .|.|.|     :|             :|
 Frog   373 EKVFTVQRIKTPKQIDELIEI----ESDTGTWYKR--CFVRIRTEFYGIWLTFMRCFEYPVKDNT 431

  Fly   313 LNICCIQFIIYFLAQGIFMWFPTIL-----DELGTR----NGE---------------------- 346
            :.:..:...:.|...|:.:||..::     ||..:|    ||.
 Frog   432 IKLTIVWLTLSFGYYGLSVWFSDVIKHLQADEYASRVKRFNGSTIADYKFNYTLENQIHKNAVFI 496

  Fly   347 ------------------------------NTLL--CTVLQGFNINSS------SEDEASSCSVE 373
                                          ||..  ||::....:|:.      ::.:..:|:..
 Frog   497 NDRFISMKFKSVVFQDSLFERCYFEDVTSINTYFRNCTLIDTHFVNTDLEKYKFTDSQTINCTFT 561

  Fly   374 V-----------DTSTYQVMII-IAACFVVI--YLIFAYIIDYMGKKNLLMAWMVLTMICLVALH 424
            :           |.|.|.:..: ......|:  .::.|.::|.:|:..:|...|||:.|....|.
 Frog   562 IPKIGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDKIGRLTMLGGSMVLSGISCFLLW 626

  Fly   425 YVEQFALVVIALTVVMAIG-NCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRLL 488
            :....:::|..|.|...:. :....:..:.:|.|||...|.|..|:..:.:..||:|:.|.|.|:
 Frog   627 FGTSESMMVGMLCVYNGLTISAWNSLDVVTVELYPTDKRATGFGFLNALCKGAAVLGNLIFGSLV 691

  Fly   489 -FASCDPIFWALLALVVLL--CTLGYFLPEKARSQ 520
             .....||   |||..||:  ..:|..||: .|:|
 Frog   692 GITKAIPI---LLASAVLVGGGLVGLRLPD-TRNQ 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	103/501 (21%)
sv2c	XP_002934873.1	synapt_SV2	1..725	CDD:130366	138/620 (22%)