Protein Alignment CG15221 and sv2ba

DIOPT Version :10

• Sequence 1: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001076464.1
• Gene: sv2ba / 100009626
• ZFINID: ZDB-GENE-070209-134
• Length: 689
• Species: Danio rerio
• Alignment Length: 615
• Identity: 136/615 - (22%)
• Similarity: 229/615 - (37%)
• Gaps: 120/615 - (19%)

  Fly    12 REFANMEGGREENLSEKPRPHTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMK 76
            |..|.|:......:.|:..|..:|..:...|.|||.:.|..:.||..|...||...||..:...:
Zfish    77 RREARMKARMAAEVEEETLPDQYESIMEDCGHGRFQWTLFTLLGLALMADGVECFVVSFALPSAE 141

  Fly    77 CDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLI 141
            .|:..:...:|:|....::|:::.:...|.|||..||...|.|||.|:.:.|.:|.|:......|
Zfish   142 KDMCLSNADKGMLGLIVYVGMMIGAVVWGGLADKLGRKQCLLYALAINCIFSFLSCFAQGYGFFI 206

  Fly   142 VFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVL 206
            .||..:|..|.|....|::...||.....|..|::.|..|..:..::|...|.||:|.......:
Zfish   207 FFRLCSGIGIGGSIPVVYTYYAEFLQMDKRGEHLSWLCLFWMLGGLYASFTAWGIIPHYGWGFSM 271

  Fly   207 G--MHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANNSGR--DPS 267
            |  ..|.||||.:|......:.||.|:..:||:|::||...|.||:..:||.:...|.|.  :|.
Zfish   272 GTEFQFHSWRVFVLVCFLPSVAALAGLVFMPESPRFLLESARHDEAWMILRRVHDTNWGAKGEPE 336

  Fly   268 EY----PVK----------EVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLWHTLNICCI 318
            ..    .:|          |:..|:|......:...:..|:.|....:.|.......|.|.|..:
Zfish   337 RVFQVSQIKTPQTQDDEFIEIQSETGTAFQRFMVRQMTLVKQVMKNMLSLAAPDVRLHGLFIAIV 401

  Fly   319 QFIIYFLAQGIFMWFP------------------------------TILDELGTRNGEN------ 347
            .|.:.|...|:..|||                              |:.::| .:.||.
Zfish   402 WFTMAFSYYGLGTWFPDQIKYLQFEEYESNVKIFHRERVERFHFNFTLQNQL-HKEGEYVHDRFI 465

  Fly   348 --------------------------------TLLCTVLQGFNINSSSEDEASSCSVEVDTSTYQ 380
                                            ||..||.  :|.:...:.:..:|::|..|..:.
Zfish   466 NIEIRNVKFEDSLFENCYFEDIKSTETFFENCTLKNTVF--YNTDLWEDSKFINCNLENTTFLHP 528

  Fly   381 VMIIIAACF--------VVIYL--------------IFAYIIDYMGKKNLLMAWMVLTMIC-LVA 422
            .    ..|.        ::|||              :...::|.:|:..::...|:.:.:| ...
Zfish   529 K----KGCHLNFQEENDILIYLDSFLGSLSVIPGNILAGLLMDKIGRLKIIGGSMLGSAVCTFFL 589

  Fly   423 LHYVEQFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRL 487
            |....|:|:|:.......|.......:..:.:|.||....|.....:....:|.|::.|.|.|:
Zfish   590 LLCFSQWAVVLFQCLFFAAGAAAWNGIEVVTVELYPASKRATAFGVLNGTCKLAAIISSFIFGK- 653

  Fly   488 LFASCDPIFWALLALVVLLC--TLGYFLPE 515
             |.....|...:|:...|:|  .|.:.|||
Zfish   654 -FIGITKIIPIILSFSALVCGGLLAFKLPE 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	105/502 (21%)
sv2ba	NP_001076464.1	synapt_SV2	36..689	CDD:130366	136/615 (22%)