DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango10 and Btbd6

DIOPT Version :9

Sequence 1:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001071151.2	Gene:	Btbd6 / 690367	RGDID:	1597323	Length:	539	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	80/354 - (22%)
Similarity:	142/354 - (40%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 PGGGAAAADLAGEAAGGAAGGDAAINNQANANGTSESPAKGL---------------------NS 99
            |.|...||:|...|...||......|  :||.|.:||...||                     |:
  Rat    47 PAGAKMAAELYPPAGASAATATDIAN--SNAAGAAESTKVGLCCPPCLAPAPLPPLPAPPLPDNN 109

  Fly   100 SEDLDAKRRKCRETEEGQDEASTMIDANSVLNKIANLYAEQLMSDIVLLVD----GKEFPAHRVI 160
            :.          |:...|....|:.:.|::      ::..:||:|:..:|.    .:..|||:.:
  Rat   110 NP----------ESPNWQSFHPTLRERNAL------MFNNELMADVHFIVGALGAARRVPAHKYV 158

  Fly   161 LCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQIEVTLQTVMPMLALSDK 225
            |...|.||..|.    :.:.::...|:|......|.|...:||:|..:|::...||:..|..:.|
  Rat   159 LAVGSSVFYAMF----YGDLAEVKSEIHIPDVEPAAFLVLLKYMYSDEIDLEADTVLATLYAAKK 219

  Fly   226 YNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHNDLTETLKRFLKWNLEMVAESRDF 290
            |.:..|...||:::...: :|..:..|:|  |..|...|   :||:.....:....||...|..|
  Rat   220 YIVPALAKACVNFLETSL-EAKNACVLLS--QSRLFEEP---ELTQRCWEVIDAQAEMALRSEGF 278

  Fly   291 VEMDPAILILLLQQNDLVVTSEYKLFDILQTWLLH--RREQMEATGSGGFMELIEQTVSHIRFGM 353
            .|:|...|.:::.: :.:.|.|..:|:.:..|...  :|:.:..|.... ..::.:.:..:|...
  Rat   279 CEIDRQTLEIIVTR-EALNTKEAVVFEAVLNWAEAECKRQGLPVTPHNK-RHVLGRALYLVRIPT 341

  Fly   354 MT-------PRQLSHLLMDPLVEYHKEFL 375
            ||       |.|...|.::   |.|..||
  Rat   342 MTLEEFANGPAQSDILTLE---ETHNIFL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	28/107 (26%)
		BTB	144..242	CDD:197585	26/101 (26%)
		BACK	258..359	CDD:197943	21/109 (19%)
Btbd6	NP_001071151.2	BTB	130..233	CDD:279045	28/106 (26%)
		BTB	138..237	CDD:197585	26/102 (25%)
		BACK	243..349	CDD:197943	23/112 (21%)
		PHR	394..537	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900