DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango10 and btbd3b

DIOPT Version :9

Sequence 1:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_003199784.1	Gene:	btbd3b / 562593	ZFINID:	ZDB-GENE-041210-282	Length:	517	Species:	Danio rerio

Alignment Length:	278	Identity:	64/278 - (23%)
Similarity:	118/278 - (42%)	Gaps:	34/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ANANGTSESPAKGLNSSEDLDAKRRKCRETEEGQDEASTMIDANSVLNKIANLYAEQLMSDIVLL 148
            |:|....:...:.||::..:..    |    ..|...||:.:.|||      ::..:||:|:..:
Zfish    70 ASATTVQQYQQQNLNNNNTIQC----C----NWQGLYSTIRERNSV------MFNNELMADVHFV 120

  Fly   149 V----DGKEFPAHRVILCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQI 209
            |    ..:..|.|:.:|...|.||..|.    :.|.::...|:.........|...:||:|..:|
Zfish   121 VGQSGGTQRLPGHKYVLAVGSSVFHAMF----YGELAEDTDEIRIPDVEPPAFLAMLKYIYCDEI 181

  Fly   210 EVTLQTVMPMLALSDKYNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHNDLTETLK 274
            :::..||:..|..:.||.:..|...||:::...:: |..:..|:|  |..|...|   |||:...
Zfish   182 DLSADTVLATLYAAKKYIVPHLARACVNFLETSLS-AKNACILLS--QSCLFEEP---DLTQRCW 240

  Fly   275 RFLKWNLEMVAESRDFVEMDPAILILLLQQNDLVVTSEYKLFDILQTWL---LHRREQMEATGSG 336
            ..:....|:..:|..|.::|...|..:|::..| ...|..:|:...:|.   ..|||.  .|...
Zfish   241 EVIDAQAELALKSDGFCDIDSQTLESILRRETL-NAKEIVVFEAALSWADAECQRREM--NTSID 302

  Fly   337 GFMELIEQTVSHIRFGMM 354
            ...:::.|::..||...|
Zfish   303 NKRKVLGQSIYLIRIPTM 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	26/107 (24%)
		BTB	144..242	CDD:197585	24/101 (24%)
		BACK	258..359	CDD:197943	23/100 (23%)
btbd3b	XP_003199784.1	BTB	108..211	CDD:279045	26/106 (25%)
		BTB	116..215	CDD:197585	24/102 (24%)
		BACK	221..327	CDD:197943	26/108 (24%)
		PHR	372..515	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900