DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango10 and Btbd6

DIOPT Version :9

Sequence 1:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_964008.2	Gene:	Btbd6 / 399566	MGIID:	3026623	Length:	539	Species:	Mus musculus

Alignment Length:	307	Identity:	71/307 - (23%)
Similarity:	124/307 - (40%)	Gaps:	57/307 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GGGGAGAGPGG---GPGGGAAAADLAGEAAGGAAGGDAAINNQANANGTSESPAKGL-------- 97
            |....||.|..   .|.....||:|...|:..||......|  :||.|.:||...||
Mouse    32 GAKARGAAPTSAEPAPAVAKMAAELYPPASPSAATATDIAN--SNAAGAAESTKVGLCCPPCLAP 94

  Fly    98 -------------NSSEDLDAKRRKCRETEEGQDEASTMIDANSVLNKIANLYAEQLMSDIVLLV 149
                         |::.          |:...|....|:.:.|::      ::..:||:|:..:|
Mouse    95 APLPPLPAPPLPDNNNP----------ESPNWQSFHPTLRERNAL------MFNNELMADVHFIV 143

  Fly   150 D----GKEFPAHRVILCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQIE 210
            .    .:..|||:.:|...|.||..|.    :.:.::...|:|......|.|...:||:|..:|:
Mouse   144 GALGAARRVPAHKYVLAVGSSVFYAMF----YGDLAEVKSEIHIPDVEPAAFLVLLKYMYSDEID 204

  Fly   211 VTLQTVMPMLALSDKYNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHNDLTETLKR 275
            :...||:..|..:.||.:..|...||:::...: :|..:..|:|  |..|...|   :||:....
Mouse   205 LEADTVLATLYAAKKYIVPALAKACVNFLETSL-EAKNACVLLS--QSRLFEEP---ELTQRCWE 263

  Fly   276 FLKWNLEMVAESRDFVEMDPAILILLLQQNDLVVTSEYKLFDILQTW 322
            .:....||...|..|.|:|...|.:::.: :.:.|.|..:|:.:..|
Mouse   264 VIDAQAEMALRSEGFCEIDRQTLEIIVTR-EALNTKEAVVFEAVLNW 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	28/107 (26%)
		BTB	144..242	CDD:197585	26/101 (26%)
		BACK	258..359	CDD:197943	15/65 (23%)
Btbd6	NP_964008.2	BTB	130..233	CDD:279045	28/106 (26%)
		BTB	138..237	CDD:197585	26/102 (25%)
		BACK	243..349	CDD:197943	18/73 (25%)
		PHR	394..537	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900