Protein Alignment Tango10 and BTBD17

DIOPT Version :10

• Sequence 1: NP_572743.1
• Gene: Tango10 / 32125
• FlyBaseID: FBgn0030330
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_011523093.1
• Gene: BTBD17 / 388419
• HGNCID: 33758
• Length: 479
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 137/513 - (26%)
• Similarity: 218/513 - (42%)
• Gaps: 76/513 - (14%)

  Fly   105 AKRRKCRETEEGQDE-----------------ASTMID-ANSVLNKIANLYAEQLMSDIVLLVDG 151
            |.|..|||.|..|.|                 |.|.|: :.:||.::..|..:...||:||.|..
Human     8 APRLFCREPETFQGEARLALLGAQRADVGGEAAGTSINHSQAVLQRLQELLRQGNASDVVLRVQA 72

  Fly   152 ------KEFPAHRVILCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQIE 210
                  :.|.|||::|...|::|..:|.|.     |:.|  |.|...|:|||.:||:|||.|::.
Human    73 AGTDEVRVFHAHRLLLGLHSELFLELLSNQ-----SEAV--LQEPQDCAAVFDKFIRYLYCGELT 130

  Fly   211 VTLQTVMPMLALSDKYNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHND-LTETLK 274
            |.|...:|:..|:.||.:..|.....|||..|:|..|  |..|.|..|.:.   |.:: |.|:..
Human   131 VLLTQAIPLHRLATKYGVSSLQRGVADYMRAHLAGGA--GPAVGWYHYAVG---TGDEALRESCL 190

  Fly   275 RFLKWNLEMVAESRDFVEMDPAILILLLQQNDLVVTSEYKLFDILQTWLLHRREQMEATGSGGFM 339
            :||.|||..||.|.::..:.|.:|..|||::|||:..|.:||..|:.||...|..         .
Human   191 QFLAWNLSAVAASTEWGAVSPELLWQLLQRSDLVLQDELELFHALEAWLGRARPP---------P 246

  Fly   340 ELIEQTVSHIRFGMMTPRQLSHL-LMDPLVEYHKEFLVERIAIGMSYQSGHEDRVREVRATESGK 403
            .:.|:.:..||:.|:.|.||..| .....:..|...:.:.:.  .:||......:...:..:...
Human   247 AVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLL--QAYQFHAASPLHYAKFFDVNG 309

  Fly   404 LQFTPRLYWNDTWSVDIDVHNFTAIEDYKNYVTCFFSQRHIAETEEDDPCMTWEIEFFPRGVRYN 468
            ..|.||.|....|.....::|....:...::.|......|.|...     :||.:.|.||.:..:
Human   310 SAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRR-----VTWNVLFSPRWLPVS 369

  Fly   469 KAKMVW----GEDVPGCSLNTVRLRVTCKHQNIGEERFKIA---VLIVGMQNQIMHIRTVVERTE 526
             .:.|:    |..:|.......|.|:.....:.|.:...::   .::||.:.|   .|.:|....
Human   370 -LRPVYADAAGTALPAARPEDGRPRLVVTPASSGGDAAGVSFQKTVLVGARQQ---GRLLVRHAY 430

  Fly   527 YFSDTSRVVNLDNLLPYEELE-HTSLYLSPHLTGTARNTLTLHVVITPMGSHTCRDTP 583
            .|..:|.  ...:.|.:.:|: ..|.||       ..|.|.||:::.|: .||...||
Human   431 SFHQSSE--EAGDFLAHADLQRRNSEYL-------VENALHLHLIVKPV-YHTLIRTP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_572743.1	BTB_POZ_BTBD17	126..239	CDD:349601	39/118 (33%)
		BACK_BTBD17	250..323	CDD:350568	27/73 (37%)
BTBD17	XP_011523093.1	BTB_POZ_BTBD17	47..159	CDD:349601	39/118 (33%)
		BACK_BTBD17	167..239	CDD:350568	28/76 (37%)