DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tango10 and Btbd3

DIOPT Version :9

Sequence 1:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001101252.1	Gene:	Btbd3 / 311462	RGDID:	1311623	Length:	528	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	64/292 - (21%)
Similarity:	113/292 - (38%)	Gaps:	61/292 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 AGEAAGGAAGGDAAINNQANANGTSESP------------------------AKGLNSSE---DL 103
            |..::||.:||         ::|:|:.|                        .|..|||.   .|
  Rat    33 ANSSSGGGSGG---------SSGSSKLPPVCYEIITLKTKKKKKMAADIFPRKKPANSSSTTVQL 88

  Fly   104 DAKRRKCRE----TEEGQDEASTMIDANSVLNKIANLYAEQLMSDIVLLV----DGKEFPAHRVI 160
            ..:...|..    ....|....|:.:.|:|      ::...||:|:..:|    ..:..|.|:.:
  Rat    89 QHQHNLCNNNLIPAPNWQGLYPTIRERNAV------MFNNDLMADVHFVVGPPGGTQRLPGHKYV 147

  Fly   161 LCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQIEVTLQTVMPMLALSDK 225
            |...|.||..|.    :.|.::...|:.......|.|...:||:|..:|::...||:..|..:.|
  Rat   148 LAVGSSVFHAMF----YGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKK 208

  Fly   226 YNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHNDLTETLKRFLKWNLEMVAESRDF 290
            |.:..|...||:::...:: |..:..|:|  |..|...|   |||:.....:....|:..:|..|
  Rat   209 YIVPHLARACVNFLETSLS-AKNACVLLS--QSCLFEEP---DLTQRCWEVIDAQAELALKSEGF 267

  Fly   291 VEMDPAILILLLQQNDLVVTSEYKLFDILQTW 322
            .::|...|..:|::..| ...|..:|:....|
  Rat   268 CDIDFQTLESILRRETL-NAKEIVVFEAALNW 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	27/107 (25%)
		BTB	144..242	CDD:197585	25/101 (25%)
		BACK	258..359	CDD:197943	15/65 (23%)
Btbd3	NP_001101252.1	BTB	119..222	CDD:279045	27/106 (25%)
		BTB	127..226	CDD:197585	25/102 (25%)
		BACK	232..338	CDD:197943	18/73 (25%)
		PHR	383..526	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900