DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango10 and Btbd3

DIOPT Version :9

Sequence 1:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_663509.2	Gene:	Btbd3 / 228662	MGIID:	2385155	Length:	530	Species:	Mus musculus

Alignment Length:	315	Identity:	68/315 - (21%)
Similarity:	118/315 - (37%)	Gaps:	63/315 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GADGAGGAGGGGGCGAGGGGAGAGPGGGP------------GGGAAAADLAGEAAGGAAGGDAAI 80
            |:..|..:||||    |||..|:|....|            .....|||:.
Mouse    29 GSKKANSSGGGG----GGGSVGSGSSKLPPVCYEIITLKTKKKKKMAADIF-------------- 75

  Fly    81 NNQANANGTSESPAKGLNSSEDLDAKRRKCRE----TEEGQDEASTMIDANSVLNKIANLYAEQL 141
                    ..:.||...:::.....:...|..    ....|....|:.:.|:|      ::...|
Mouse    76 --------PRKKPANSSSTTVQQQHQHNLCNNNLIPAPNWQGLYPTIRERNAV------MFNNDL 126

  Fly   142 MSDIVLLV----DGKEFPAHRVILCASSDVFQVMLMNPEWNECSKHVIELHEEACCSAVFPQFIK 202
            |:|:..:|    ..:..|.|:.:|...|.||..|.    :.|.::...|:.......|.|...:|
Mouse   127 MADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMF----YGELAEDKDEIRIPDVEPAAFLAMLK 187

  Fly   203 YLYVGQIEVTLQTVMPMLALSDKYNIRDLIDLCVDYMNKHVAKAATSGYLVSWLQYTLSFTPTHN 267
            |:|..:|::...||:..|..:.||.:..|...||:::...:: |..:..|:|  |..|...|
Mouse   188 YIYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLS-AKNACVLLS--QSCLFEEP--- 246

  Fly   268 DLTETLKRFLKWNLEMVAESRDFVEMDPAILILLLQQNDLVVTSEYKLFDILQTW 322
            |||:.....:....|:..:|..|.::|...|..:|::..| ...|..:|:....|
Mouse   247 DLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETL-NAKEIVVFEAALNW 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	27/107 (25%)
		BTB	144..242	CDD:197585	25/101 (25%)
		BACK	258..359	CDD:197943	15/65 (23%)
Btbd3	NP_663509.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..48		10/22 (45%)
		BTB	121..224	CDD:279045	27/106 (25%)
		BTB	129..228	CDD:197585	25/102 (25%)
		BACK	234..340	CDD:197943	18/73 (25%)
		PHR	385..528	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900