DRSC/TRiP Functional Genomics Resources

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Protein Alignment prtp and EPS1

DIOPT Version :9

Sequence 1:NP_001188583.1 Gene:prtp / 32124 FlyBaseID:FBgn0030329 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_012261.1 Gene:EPS1 / 854812 SGDID:S000001267 Length:701 Species:Saccharomyces cerevisiae


Alignment Length:284 Identity:62/284 - (21%)
Similarity:112/284 - (39%) Gaps:59/284 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LTRSILSVAVCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGNVFVKFFAPWCG 66
            |.|.:::...|   ::.||..|.|:.|...|     |...|:|..|...::.|...:.|::|:|.
Yeast     5 LKRLVVTFFSC---ITFLLKFTIAAAEPPEG-----FPEPLNPTNFKEELSKGLHIIDFYSPYCP 61

  Fly    67 HCKRIQPLWEQLAEIMNVDNP--KVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKG 129
            |||.:.|:|.:..|....::.  .:..::|:|.:...||....:..:|.:||:    ..|...|.
Yeast    62 HCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLY----NPSGYIKS 122

  Fly   130 TRDLP----AITDFINKELSAP--AEADLGEVKREQ--VENLNIGKVVDLTEDTFAKHVSTGNHF 186
            ..:.|    ::..|..:|...|  .:.||...|.|.  :|..      |..|....|  :|..|.
Yeast   123 FTETPRTKESLIAFARRESMDPNNLDTDLDSAKSESQYLEGF------DFLELIAGK--ATRPHL 179

  Fly   187 VKFFAPW----------------CSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFE 235
            |.|   |                |..|.....||:.::::|..: .:....::|....:||::. 
Yeast   180 VSF---WPTKDMKNSDDSLEFKNCDKCHEFQRTWKIISRQLAVD-DINTGHVNCESNPTICEEL- 239

  Fly   236 VKGYPTLLWIEDGKKIEKYSGARD 259
              |:..|:      ||..:...|:
Yeast   240 --GFGDLV------KITNHRADRE 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
prtpNP_001188583.1 PDI_a_ERp46 38..140 CDD:239303 24/107 (22%)
ER_PDI_fam 39..409 CDD:273457 52/247 (21%)
PDI_a_ERp46 167..267 CDD:239303 21/109 (19%)
PDI_a_ERp46 303..407 CDD:239303
EPS1NP_012261.1 Thioredoxin 33..139 CDD:395038 25/109 (23%)
PTZ00102 <404..>472 CDD:240266
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0191
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_104137
Panther 1 1.100 - - LDO PTHR45672
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.810

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