DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prtp and MPD1

DIOPT Version :9

Sequence 1:	NP_001188583.1	Gene:	prtp / 32124	FlyBaseID:	FBgn0030329	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_014931.3	Gene:	MPD1 / 854462	SGDID:	S000005814	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	143	Identity:	46/143 - (32%)
Similarity:	73/143 - (51%)	Gaps:	36/143 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 KLTPQQLTGEDEFDQAI--AEGVAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCT 363
            :|||:      .||:||  ....:.::|||||||||:||..|:.:.|   .:....|::|.|:|.
Yeast    33 ELTPK------SFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAA---KRLDGVVQVAAVNCD 88

  Fly   364 APENKQVCIDQQVEGYPTLFLYK-----------NGQRQ-----NE-YEGSR--------SLPEL 403
            ..:||.:|....|.|:|||.:::           |.::.     || |.|:|        ||..:
Yeast    89 LNKNKALCAKYDVNGFPTLMVFRPPKIDLSKPIDNAKKSFSAHANEVYSGARTLAPIVDFSLSRI 153

  Fly   404 QAYLKKFLGHDEL 416
            ::|:|||:..|.|
Yeast   154 RSYVKKFVRIDTL 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303
		ER_PDI_fam	39..409	CDD:273457	41/134 (31%)
		PDI_a_ERp46	167..267	CDD:239303
		PDI_a_ERp46	303..407	CDD:239303	39/130 (30%)
MPD1	NP_014931.3	ER_PDI_fam	30..>275	CDD:273457	46/143 (32%)
MPD1	NP_014931.3	PDI_a_MPD1_like	30..150	CDD:239300	38/125 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810