DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prtp and UNE5

DIOPT Version :9

Sequence 1:	NP_001188583.1	Gene:	prtp / 32124	FlyBaseID:	FBgn0030329	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_182269.1	Gene:	UNE5 / 819360	AraportID:	AT2G47470	Length:	361	Species:	Arabidopsis thaliana

Alignment Length:	306	Identity:	95/306 - (31%)
Similarity:	153/306 - (50%)	Gaps:	41/306 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SILSVAVCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGNVFVKFFAPWCGHCK 69
            ::|::.:...:...::.:|..|.|::.|| ||                  ...|:|:||||||||
plant    11 ALLALLLVSAVADDVVVLTDDSFEKEVGK-DK------------------GALVEFYAPWCGHCK 56

  Fly    70 RIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLP 134
            ::.|.:|:|..... ....|:||||||.:.:.:|..:.|:||||::.|..|..|..|::|.|:..
plant    57 KLAPEYEKLGASFK-KAKSVLIAKVDCDEQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAE 120

  Fly   135 AITDFINKELSAPAEADLGEVKREQVENLNIGKVVDLTEDTFAKHVSTGNH--FVKFFAPWCSHC 197
            |:.:::|||...       .||...|..    .||.||.|.|.:.|...|.  .|:|:||||.||
plant   121 ALAEYVNKEGGT-------NVKLAAVPQ----NVVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHC 174

  Fly   198 QRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFEVKGYPTLLWI-EDGKKIEKYSGARDLS 261
            :.||||:|.:|....:|..|.|:.:|....:::.:.:.|.|:|||.:. :|.|....|.|.|||.
plant   175 KSLAPTYEKVATVFKQEEGVVIANLDADAHKALGEKYGVSGFPTLKFFPKDNKAGHDYDGGRDLD 239

  Fly   262 TLKTYVEKMVGVPLE---KTAGEAGD----EKVVIEEVAGEEDAAK 300
            ...:::.:..|...:   :...:||.    :.:|.|.||..||..|
plant   240 DFVSFINEKSGTSRDSKGQLTSKAGIVESLDALVKELVAASEDEKK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	33/101 (33%)
		ER_PDI_fam	39..409	CDD:273457	87/272 (32%)
		PDI_a_ERp46	167..267	CDD:239303	38/102 (37%)
		PDI_a_ERp46	303..407	CDD:239303
UNE5	NP_182269.1	PDI_a_ERp38	28..126	CDD:239296	40/117 (34%)
		PDI_a_ERp38	142..245	CDD:239296	38/102 (37%)
		ERp29c	266..357	CDD:238146	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810