Protein Alignment prtp and pdia4

DIOPT Version :9

• Sequence 1: NP_001188583.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_956073.2
• Gene: pdia4 / 554998
• ZFINID: ZDB-GENE-030131-5493
• Length: 642
• Species: Danio rerio
• Alignment Length: 619
• Identity: 147/619 - (23%)
• Similarity: 228/619 - (36%)
• Gaps: 258/619 - (41%)

  Fly    29 EDTGKQDKQFTVELDPETFDTAIAG-GNVFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKVIIA 92
            :||..:::...:.|....|||.|.| ..|.|:|:||||||||:..|.:|::|:.:..::|.:.:|
Zfish    51 DDTEVKEENGVLVLTDANFDTFIEGKDTVLVEFYAPWCGHCKQFAPEYEKIAQTLKENDPPIPVA 115

  Fly    93 KVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDFINKELS-----APAEADL 152
            |||.||..||.:..:|:||||:::.|.|  |.:.:.|.|...||.:.: ||::     .|.||.|
Zfish   116 KVDATKASGLGSRFEVSGYPTIKILKKG--EPLDYDGDRSEHAIVERV-KEVAQPDWKPPPEATL 177

  Fly   153 GEVKREQVENLNIGKVVDLTEDTFAKHVSTGN-HFVKFFAPWCSHCQRLAPTWEDLAKELI-KEP 215
                             .||:|.|...|:..: ..|:|:||||.||:||||.:|..||||. :.|
Zfish   178 -----------------VLTKDNFDDVVNNADIILVEFYAPWCGHCKRLAPEYEKAAKELSNRTP 225

  Fly   216 TVTISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVGVPLE---- 276
            .:.::|:|.|....:...|.|.|||||.....||..: |:|.|:...:..|:....|.|.:
Zfish   226 PIPLAKVDATAESDLATRFGVSGYPTLKIFRKGKAFD-YNGPREKFGIVDYMSDQAGPPSKQVQT 289

  Fly   277 -KTAGEA---GDEKVVIEEVAGEEDAA-------------------------------------- 299
             |...|.   ||:.|::...:.:||||
Zfish   290 LKQVQELLRDGDDAVIVGVFSSDEDAAYEIYQEACNSLREDYKFMHTFNNDVTKFLKASPGQVVM 354

  Fly   300 -------------------KKLTPQQ--------------------------------------- 306
                               |..||..
Zfish   355 LQPEKFRSKYESASHSLTIKDSTPASEVQDFFKKHILPLVGHRKQSNDAKRYTKRPLVVVYYGVD 419

  Fly   307 -------------------------------------------------------LTGE------ 310
                                                                   :.||
Zfish   420 FSFDYRVATQFWRSKVLEVAKDFPEYTFAIADEEDYADELKSLGLSESGEEVNVGIVGEGGKKYA 484

  Fly   311 ---DEFDQAIAEG--VAF------------------------------------------IKFYA 328
               :|||..:...  :||                                          |:|||
Zfish   485 MEPEEFDSDVLRSFVMAFKKGKLKPIVKSQPLPKNNKGPVKVVVGKTFDEIVMDSKKDVLIEFYA 549

  Fly   329 PWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTA---PENKQVCIDQQVEGYPTLFLYKNGQR 390
            ||||||:||:|.:..|. :.::.:.::.|||:|.||   |.:     ..:|||:||::...:..:
Zfish   550 PWCGHCKKLEPDYISLG-KKYKNEKNLVIAKMDATANDVPHD-----SYKVEGFPTIYFAPSNNK 608

  Fly   391 QN--EYE-GSRSLPELQAYLKKF---LGH--DEL 416
            ||  ::| |.|.:.|...:::|.   |.|  |||
Zfish   609 QNPIKFEGGKRDVEEFSKFVEKHATKLSHKKDEL 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	41/102 (40%)
		ER_PDI_fam	39..409	CDD:273457	139/595 (23%)
		PDI_a_ERp46	167..267	CDD:239303	38/101 (38%)
		PDI_a_ERp46	303..407	CDD:239303	41/256 (16%)
pdia4	NP_956073.2	pdi_dom	64..165	CDD:273454	43/103 (42%)
		ER_PDI_fam	174..640	CDD:273457	98/489 (20%)
		pdi_dom	179..280	CDD:273454	39/101 (39%)
		PDI_b_ERp72	283..389	CDD:239366	13/105 (12%)
		PDI_b'_ERp72_ERp57	394..503	CDD:239371	6/108 (6%)
		PDI_a_PDI_a'_C	523..628	CDD:239293	32/110 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910