Protein Alignment prtp and P4HB

DIOPT Version :9

• Sequence 1: NP_001188583.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_024306545.1
• Gene: P4HB / 5034
• HGNCID: 8548
• Length: 546
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 99/434 - (22%)
• Similarity: 169/434 - (38%)
• Gaps: 104/434 - (23%)

  Fly     1 MLTRSILSVAVCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGN-VFVKFFAPW 64
            ||.|::|.:||..|:.:.      |.:|||       ..:.|....|..|:|... :.|:|:|||
Human     1 MLRRALLCLAVAALVRAD------APEEED-------HVLVLRKSNFAEALAAHKYLLVEFYAPW 52

  Fly    65 CGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVK-FK 128
            |||||.:.|.:.:.|..:..:..::.:||||.|:...|...:.|.||||::.|:.|:..|.| :.
Human    53 CGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYT 117

  Fly   129 GTRDLPAITDFINKELSAPAEADL--GEVKREQVENLNIGKV----------------------- 168
            ..|:...|.:::.|. :.||...|  |......||:..:..:
Human   118 AGREADDIVNWLKKR-TGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDD 181

  Fly   169 ----VDLTEDTFAKHVSTGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTVTISK-------I 222
                :....|.|:|:....:..|.|        ::......:...|:.||..:...|       |
Human   182 IPFGITSNSDVFSKYQLDKDGVVLF--------KKFDEGRNNFEGEVTKENLLDFIKHNQLPLVI 238

  Fly   223 DCTQFRSICQDF--EVKGYPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVG------VPLEKT- 278
            :.|: ::..:.|  |:|.: .||::.  |.:..|.|  .||..||..|...|      :..:.|
Human   239 EFTE-QTAPKIFGGEIKTH-ILLFLP--KSVSDYDG--KLSNFKTAAESFKGKILFIFIDSDHTD 297

  Fly   279 -------AGEAGDEKVVIEEVAGEEDAAK-KLTPQQLTGE--DEFDQAIAEGVAFIKFYAPWCGH 333
                   .|...:|...:..:..||:..| |...::||.|  .||.....||
Human   298 NQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEG------------- 349

  Fly   334 CQKLQP--TWEQLATETHQAQSSVKIAK--VDCTAPENKQVCID 373
              |::|  ..::|..:..:....|.:.|  .|....|.|.|.::
Human   350 --KIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVE 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	33/103 (32%)
		ER_PDI_fam	39..409	CDD:273457	88/396 (22%)
		PDI_a_ERp46	167..267	CDD:239303	23/135 (17%)
		PDI_a_ERp46	303..407	CDD:239303	16/77 (21%)
P4HB	XP_024306545.1	YbbN	24..394	CDD:331940	89/405 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910