Protein Alignment prtp and pdia6

DIOPT Version :10

• Sequence 1: NP_572742.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001007974.1
• Gene: pdia6 / 493341
• XenbaseID: XB-GENE-974680
• Length: 441
• Species: Xenopus tropicalis
• Alignment Length: 284
• Identity: 57/284 - (20%)
• Similarity: 107/284 - (37%)
• Gaps: 91/284 - (32%)

  Fly   256 LEEVNNYIDILMKALHDENLLECVNLVIVSDHGMQALNNSIEVETIVNMDGLVLSKGV-----VA 315
            :.:.|.|:..|.|.:..:.|.:     :.|.:| :.:.:.|.|:.:..     :|:||     ..
 Frog   129 IRDANLYVSGLPKTMTQKELEQ-----LFSQYG-RIITSRILVDQVTG-----VSRGVGFIRFDK 182

  Fly   316 RIHLNETDRSIDEVAGEIRCKIDG----VKVNTINDIPLRK---------HYSKSKRVGDIIIEG 367
            ||   |.:.:|..:.|:   |..|    :.|...|: |.:|         :.|.::|.
 Frog   183 RI---EAEEAIKGLNGQ---KPSGATEPITVKFANN-PSQKSSQALLSQLYQSPNRRY------- 233

  Fly   368 KPGTSFYKSE----TNLGDHGYDYHN------ENMHTVMFARGPS--------FLQNVTVPSFQN 414
             ||...::::    .||.:..|....      :.|.:::....|.        |:.|::..|.::
 Frog   234 -PGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDES 297

  Fly   415 VQYMNLWLYLLGLEGTVDNNGTIGFFDSILKNPPIRENKWDSMEECLNFGSAEVLQCDKA----- 474
            |    || .|.|..|.|:|...|..|::         ||      |..||...:...|:|
 Frog   298 V----LW-QLFGPFGAVNNVKVIRDFNT---------NK------CKGFGFVTMTNYDEAAMAIA 342

  Fly   475 --EGHDL--KKLSLHLENCKEHQN 494
              .|:.|  :.|.:..:..|.|::
 Frog   343 SLNGYRLGDRVLQVSFKTNKAHKS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_572742.1	PDI_a_ERp46	38..140	CDD:239303
		PDI_a_ERp46	167..267	CDD:239303	2/10 (20%)
		PDI_a_ERp46	303..407	CDD:239303	24/139 (17%)
pdia6	NP_001007974.1	PDI_a_P5	26..128	CDD:239299
		PDI_a_P5	162..267	CDD:239299	23/124 (19%)
		P5_C	276..405	CDD:239281	26/111 (23%)