DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prtp and pdia6

DIOPT Version :9

Sequence 1:	NP_001188583.1	Gene:	prtp / 32124	FlyBaseID:	FBgn0030329	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001007974.1	Gene:	pdia6 / 493341	XenbaseID:	XB-GENE-974680	Length:	441	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	84/263 - (31%)
Similarity:	135/263 - (51%)	Gaps:	50/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 VVDLTEDTFAKHV--STGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSI 230
            |::||...|.|.|  |.....|:|:||||.|||||.|.|:..|..|  :..|.|..::..|.:|:
Frog    27 VIELTPSNFNKEVIQSDSLWLVEFYAPWCGHCQRLTPDWKKAATAL--KGVVKIGAVNADQHQSL 89

  Fly   231 CQDFEVKGYPTL-LWIEDGKKIEKYSGARD--------LSTLKTYVEKMVGVPLEKTAGE----- 281
            ...:.|:|:||: ::..:..|.:.|.|.|.        ||:|:::|:..:|   .::.|.
Frog    90 GGQYGVRGFPTIKVFGANKNKPDDYQGGRTADAIIDAALSSLRSFVKDRLG---GRSGGSDSGRQ 151

  Fly   282 -----AGDEKVVIEEVAGEEDAAKKLTPQQLTGEDEFDQAI--AEGVAFIKFYAPWCGHCQKLQP 339
                 .|.:|.||:                || :|.||:.:  ::.|.|::|||||||||:.|:|
Frog   152 SYSSGGGSKKDVID----------------LT-DDTFDKNVLNSDDVWFVEFYAPWCGHCKNLEP 199

  Fly   340 TWEQLATE-THQAQSSVKIAKVDCTAPENKQVCIDQQ-VEGYPTLFLYKNGQRQNEYEGSRSLPE 402
            .|...||| ..|....||:|.||.|.   .||...:. :.|:||:.:::.|:...:|:|.|:.|:
Frog   200 EWAAAATEIKQQTNGKVKLAAVDATV---SQVLASRYGIRGFPTIKIFQKGEDPVDYDGGRTKPD 261

  Fly   403 LQA 405
            :.|
Frog   262 IVA 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303
		ER_PDI_fam	39..409	CDD:273457	84/263 (32%)
		PDI_a_ERp46	167..267	CDD:239303	37/109 (34%)
		PDI_a_ERp46	303..407	CDD:239303	40/107 (37%)
pdia6	NP_001007974.1	PDI_a_P5	26..128	CDD:239299	34/102 (33%)
		PDI_a_P5	162..267	CDD:239299	42/123 (34%)
		P5_C	276..405	CDD:239281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000