Protein Alignment prtp and Pdi

DIOPT Version :10

• Sequence 1: NP_572742.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 114/501 - (22%)
• Similarity: 203/501 - (40%)
• Gaps: 140/501 - (27%)

  Fly    11 VCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGN-VFVKFFAPWCGHCKRIQPL 74
            :|.|.|:  .....||.|.:...::......:|  .|...||... |.|:|:||||||||.:.|.
  Fly     5 ICALFLA--ASYVAASAEAEVKVEEGVLVATVD--NFKQLIADNEFVLVEFYAPWCGHCKALAPE 65

  Fly    75 WEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDF 139
            :.:.|:.:......:.:||||.|....|...:.|.|||||:.|:.|  ..|::.|.|....|..:
  Fly    66 YAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG--SPVEYSGGRQAADIIAW 128

  Fly   140 INKELSAPAE---------------------------------------------------ADL- 152
            :.|:...||:                                                   ||:
  Fly   129 VTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVI 193

  Fly   153 ------------------------GEVKRE------QVENLNIGKVVDLTEDTFAKHV--STGNH 185
                                    ||:..|      ||::|.:  :||...::.:|..  |..:|
  Fly   194 AKYEAKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPL--IVDFNHESASKIFGGSIKSH 256

  Fly   186 FVKFFAPWCSHCQRLAPTWEDLAKEL---IKEPTVTISKIDCTQFRSICQDFEVKG-----YPTL 242
            .:.|.:....|.::.....:::||:.   |...|::..:.|.|:.      ||..|     .||:
  Fly   257 LLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRI------FEFFGMNKEEVPTI 315

  Fly   243 LWIEDGKKIEKYS-GARDLS--TLKTYVEKMVGVPLEKTAGEAGDEKVVIEEVAGEEDAAKKLTP 304
            ..|:..:.:.||. .:.|||  |::.:::|.:...|:        :.::.:|:..:.|.    .|
  Fly   316 RLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLK--------QHLLSQELPEDWDK----NP 368

  Fly   305 QQLTGEDEFDQAIAEGVA-------FIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDC 362
            .::.....|     |.||       .::|||||||||::|.|.::||| |.::....:.|||:|.
  Fly   369 VKVLVSSNF-----ESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLA-EKYKDNEDIVIAKMDS 427

  Fly   363 TAPENKQVCIDQQVEGYPTL-FLYKNGQRQNEYEGSRSLPELQAYL 407
            ||.|.:.:    ::..:||: :..|...:..::...|:|.:...:|
  Fly   428 TANELESI----KISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFL 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_572742.1	PDI_a_ERp46	38..140	CDD:239303	35/102 (34%)
		PDI_a_ERp46	167..267	CDD:239303	25/112 (22%)
		PDI_a_ERp46	303..407	CDD:239303	32/111 (29%)
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	108/477 (23%)