Protein Alignment prtp and pdi1

DIOPT Version :10

• Sequence 1: NP_572742.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_592871.1
• Gene: pdi1 / 2541460
• PomBaseID: SPAC1F5.02
• Length: 492
• Species: Schizosaccharomyces pombe
• Alignment Length: 448
• Identity: 112/448 - (25%)
• Similarity: 183/448 - (40%)
• Gaps: 124/448 - (27%)

  Fly    56 VFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLG 120
            :.|||:||||||||.:.|.:|..|:.:..|.  :.:.:||||:...||:.:.:.|||||.:||.|
pombe    42 LMVKFYAPWCGHCKALAPEYESAADELEKDG--ISLVEVDCTEEGDLCSEYSIRGYPTLNVFKNG 104

  Fly   121 EEESVKFKGTRDLPAITDFINKEL---SAPAEADLGEVKREQVENL------------------- 163
            ::.| ::.|.|...|:..::.|:|   ..|...|..|...|:.::|
pombe   105 KQIS-QYSGPRKHDALVKYMRKQLLPTVKPISKDTLENFVEKADDLAVVAFFKDQKLNDTYTEVA 168

  Fly   164 -----------------------NIGKVVDLTED------------------------------- 174
                                   |...:|..|:|
pombe   169 EVMKDDFVFAASDDKELAKSLGSNFPGIVAFTKDAAQDSDKLVYTGDWDPASIADFIGVSSIPLL 233

  Fly   175 ------TFAKHVSTGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQD 233
                  ||.|:..:|......|.........|...::.|||:.  :.|:..:.:|..::.::.:.
pombe   234 DELNQMTFGKYQQSGLPLGIIFYNSTESRDELYDVFQPLAKKY--QDTLRFAFLDAVRYGAVAKQ 296

  Fly   234 FEVKG-YPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVGVPLEKTAGEAGDEKV-------VIE 290
            ..|:. :|..: |.:.|.:.||.......|.|.         :.|..|:..|.|:       .|.
pombe   297 MNVESDWPAFV-IANLKSMLKYPFPTTELTAKA---------MTKFVGDFVDGKLQPKIKSQPIP 351

  Fly   291 EVAGEEDAAKKLTPQQLTGEDEFDQAIAEGV--AFIKFYAPWCGHCQKLQPTWEQLATETHQAQS 353
            |  .:||....:.       |.||..:.:..  ..::|||||||||:.|.||:|:|| |.:...|
pombe   352 E--SQEDLVVLVA-------DNFDDIVMDETKDVLVEFYAPWCGHCKNLAPTYEKLA-EEYSDDS 406

  Fly   354 SVKIAKVDCTAPENKQVCIDQQVEGYPTLFLYKNGQRQN--EYEGSRSLPELQAYLKK 409
            :|.:||:|.|  ||.   |...:.|:||:..:|...:.|  .|||.|:|.:|.|::.|
pombe   407 NVVVAKIDAT--END---ISVSISGFPTIMFFKANDKVNPVRYEGDRTLEDLSAFIDK 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_572742.1	PDI_a_ERp46	38..140	CDD:239303	33/83 (40%)
		PDI_a_ERp46	167..267	CDD:239303	22/137 (16%)
		PDI_a_ERp46	303..407	CDD:239303	40/107 (37%)
pdi1	NP_592871.1	ER_PDI_fam	23..464	CDD:273457	112/448 (25%)