Protein Alignment prtp and tmx3

DIOPT Version :10

• Sequence 1: NP_572742.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_002939661.2
• Gene: tmx3 / 100493559
• XenbaseID: XB-GENE-946768
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 314
• Identity: 69/314 - (21%)
• Similarity: 134/314 - (42%)
• Gaps: 59/314 - (18%)

  Fly     6 ILSVAVCGLLLSPLLPITRASQE-EDTGKQDKQFTVELDPETFDTAIAGGNVFVKFFAPWCGHCK 69
            :.:||...||.|  ||::...:: :|:.|::::..:.|               |.|:||||||||
 Frog    10 LATVASTSLLAS--LPVSALVEDLDDSFKENRKDDIWL---------------VDFYAPWCGHCK 57

  Fly    70 RIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLP 134
            :::|:|.::...|......:.:.|:|.|.|..:.:...|.|:||:::.|  .:.:..::|.|...
 Frog    58 KLEPVWNEVGIEMRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLK--GDMAYNYRGPRTKE 120

  Fly   135 AITDFINKELS-----APAEADLGEV-KREQVENLNIGKVVDLTEDTFAKHVSTGNHFVKFFAPW 193
            .|.:|.|:...     .|::.....| ||..|..:.:|....|.|    |::...:..: .:..:
 Frog   121 DIVEFANRVAGPLIRPLPSQQMFDHVQKRHSVLFVYVGVESTLKE----KYIEVASELI-VYTYF 180

  Fly   194 CSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYSGAR 258
            .|..:.:.|.:..|.    :.|.|.:.| |.|.|  :..::|.....:  |:..    |::.|..
 Frog   181 FSASEDVLPKYVTLN----EVPAVLVFK-DSTYF--VYDEYEDGDLSS--WVNK----ERFEGYL 232

  Fly   259 DLSTLKTYVEKMVGVPLEKTAGEAGDE-KVVIEEVAGEEDAAKKLTPQQLTGED 311
            .:.....|              |.||. |:|...|..|::.:.:.|..:...:|
 Frog   233 HIDGFTLY--------------ELGDTGKLVAVAVIDEKNNSVEHTRLKSIAQD 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prtp	NP_572742.1	PDI_a_ERp46	38..140	CDD:239303	26/101 (26%)
		PDI_a_ERp46	167..267	CDD:239303	16/99 (16%)
		PDI_a_ERp46	303..407	CDD:239303	2/9 (22%)
tmx3	XP_002939661.2	PDI_a_TMX3	27..130	CDD:239298	30/119 (25%)
		ER_PDI_fam	29..>346	CDD:273457	62/293 (21%)