Protein Alignment FucT6 and FUT8

DIOPT Version :9

• Sequence 1: NP_572740.1
• Gene: FucT6 / 32122
• FlyBaseID: FBgn0030327
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001358465.1
• Gene: FUT8 / 2530
• HGNCID: 4019
• Length: 609
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 280/642 - (43%)
• Similarity: 391/642 - (60%)
• Gaps: 83/642 - (12%)

  Fly    14 SWARALIIFVLAWIGLVYVFVVKLTNTQGQQAAGESELNARRISQALQMLEHTRQRNEELKQLID 78
            || |.:::.:.||..|::.....|....     ...:.::|.:|:.|..||..:|:||:|:::.:
Human     7 SW-RWIMLILFAWGTLLFYIGGHLVRDN-----DHPDHSSRELSKILAKLERLKQQNEDLRRMAE 65

  Fly    79 ELMSDQ--LDKQSAMKLVQRLENDALNPKLAPEVAGPEPESMFESAPADLRGWNNVAEGAPNDLE 141
            .|...:  :|:..|:..|:.||...:..|...|                     |..:...|.|
Human    66 SLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIE---------------------NYKKQTRNGL- 108

  Fly   142 AGVPDHGEFEPSLEYEFTRRRIQTNIGEIWNFFSSELGKVRKAVAAGHASADLEESINQVLLQGA 206
                       ..::|..||||:....|:|.|..|||.|::..     ...:|:...::.||...
Human   109 -----------GKDHEILRRRIENGAKELWFFLQSELKKLKNL-----EGNELQRHADEFLLDLG 157

  Fly   207 EHKR----------------------------------SLLSDMERMRQSDGYEAWRHKEARDLS 237
            .|:|                                  |:::|:..:.|:||...||.|||:||:
Human   158 HHERILMAITVSLVNNKRKIVVLAQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLT 222

  Fly   238 DLVQRRLHHLQNPSDCQNARKLVCKLNKGCGYGCQLHHVVYCFIVAYATERTLILKSRGWRYHKG 302
            :|||||:.:||||.||..|:||||.:|||||||||||||||||::||.|:|||||:|:.|||..|
Human   223 ELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATG 287

  Fly   303 GWEEVFQPVSNSCHDAGTANTYNWPGK---PNTQVLVLPIIDSLMPRPPYLPLAVPEDLAPRLKR 364
            |||.||:|||.:|.|....:|.:|.|:   .|.||:.|||:|||.|||||||||||||||.||.|
Human   288 GWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVR 352

  Fly   365 LHGDPIVWWVGQFLKYLLRPQPTTRDFLTSGMRNLGWERPIVGVHVRRTDKVGTEAACHSVEEYM 429
            :||||.||||.||:|||:||||.....:....:.||::.|::|||||||||||||||.|.:||||
Human   353 VHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYM 417

  Fly   430 TYVEDYYRTLEVNGSTVARRIFLASDDAQVIEEARRKYPQYQIIGDPEVARMASVSTRYTDTALN 494
            .:||::::.|........:|::||:||..:::||:.|||.|:.|.|..::..|.:..|||:.:|.
Human   418 VHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLR 482

  Fly   495 GIILDIHLLSMSDHLVCTFSSQVCRVAYEIMQTMYPDAAHRFKSLDDIYYYGGQNAHNRRVVIAH 559
            |:|||||.||.:|.|||||||||||||||||||::|||:..|.|||||||:|||||||:..:.||
Human   483 GVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAH 547

  Fly   560 KPRTHEDLQLRVGDLVSVAGNHWDGNSKGKNTRTNQGGLFPSFKVEEKVDTAKLPLY 616
            :|||.:::.:..||::.||||||||.|||.|.:..:.||:||:||.||::|.|.|.|
Human   548 QPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTY 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FucT6	NP_572740.1	Fut8_like	223..545	CDD:211386	194/324 (60%)
		SH3_Fut8	552..606	CDD:212726	26/53 (49%)
FUT8	NP_001358465.1	AlaS	<50..179	CDD:223092	34/166 (20%)
		Fut8_like	208..533	CDD:211386	194/324 (60%)
		SH3_Fut8	540..594	CDD:212726	26/53 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141473
Domainoid	1	1.000	488	1.000	Domainoid score	I390
eggNOG	1	0.900	-	-		E1_KOG3705
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9650
Inparanoid	1	1.050	561	1.000	Inparanoid score	I1097
Isobase	1	0.950	-	0	Normalized mean entropy	S3633
OMA	1	1.010	-	-		QHG48759
OrthoDB	1	1.010	-	-		D1290594at2759
OrthoFinder	1	1.000	-	-		FOG0006332
OrthoInspector	1	1.000	-	-		oto91589
orthoMCL	1	0.900	-	-		OOG6_105427
Panther	1	1.100	-	-	LDO	PTHR13132
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4607
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720