DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FucT6 and fut8b

DIOPT Version :9

Sequence 1:	NP_572740.1	Gene:	FucT6 / 32122	FlyBaseID:	FBgn0030327	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	XP_005173879.1	Gene:	fut8b / 100331714	ZFINID:	ZDB-GENE-130530-923	Length:	580	Species:	Danio rerio

Alignment Length:	610	Identity:	282/610 - (46%)
Similarity:	385/610 - (63%)	Gaps:	52/610 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SWARALIIFVLAWIGLVYVFVVKLTNTQGQQAAGESE---LNARRISQALQMLEHTRQRNEELKQ 75
            || |.:.:.:|||..|::..        |.....:||   .::|.:::.|..||..:|:||:|::
Zfish     7 SW-RWIALVLLAWGTLLFYI--------GGHLVKDSEHAPRSSRELAKILTKLERLKQQNEDLRR 62

  Fly    76 LIDELMSDQLDKQSAMKLVQRLENDALNPKLAPEVAGPEPESMFESAPADLRGWNNVAEGAPNDL 140
            :...|               |:               ||.:|....:...||........|...:
Zfish    63 MAQSL---------------RI---------------PEGQSDGPISSGRLRSLEEQLSRAKQKI 97

  Fly   141 EAGVPDHGEFEPSLEYEFTRRRIQTNIGEIWNFFSSELGKVRKAVAAGHASADLEESINQVLLQG 205
            ::.....||..|..|.|..||:::..:.|:|.|..||:.|:      .|.:....:.....|||.
Zfish    98 QSFQRLSGEAGPGREQEELRRKVENGVRELWYFIHSEIQKL------SHVNPTDRQKQTDALLQD 156

  Fly   206 AEH-KRSLLSDMERMRQSDGYEAWRHKEARDLSDLVQRRLHHLQNPSDCQNARKLVCKLNKGCGY 269
            ..| :|::::|:..:.|:||...||.|||||||.|||.|:..||||.||..||||||.:||||||
Zfish   157 LGHQQRAIMTDLHELAQADGAGEWRDKEARDLSILVQNRISFLQNPQDCSKARKLVCNINKGCGY 221

  Fly   270 GCQLHHVVYCFIVAYATERTLILKSRGWRYHKGGWEEVFQPVSNSCHDAGTANTYNWPGKP---N 331
            |||||||||||::||.|:|.|||:|..|||...|||.||:.||.:|.|...|.|.:|.|:.   :
Zfish   222 GCQLHHVVYCFMIAYGTQRVLILESHNWRYAPKGWETVFKAVSETCTDRSGATTGHWSGEAHDRD 286

  Fly   332 TQVLVLPIIDSLMPRPPYLPLAVPEDLAPRLKRLHGDPIVWWVGQFLKYLLRPQPTTRDFLTSGM 396
            .||:.|||:|||.||||||||||||||||||:||||||.||||.||:|:|:|||......:....
Zfish   287 VQVVELPIVDSLHPRPPYLPLAVPEDLAPRLQRLHGDPSVWWVSQFVKFLVRPQAWLEKEIQETC 351

  Fly   397 RNLGWERPIVGVHVRRTDKVGTEAACHSVEEYMTYVEDYYRTLEVNGSTVARRIFLASDDAQVIE 461
            ..||::.||:|||||||||||||||.|.:||||.:||:.::::...|....:|::||:||..:::
Zfish   352 LKLGFKHPIIGVHVRRTDKVGTEAAFHPIEEYMVHVEEQFQSMAQRGHVDKKRVYLATDDPALLQ 416

  Fly   462 EARRKYPQYQIIGDPEVARMASVSTRYTDTALNGIILDIHLLSMSDHLVCTFSSQVCRVAYEIMQ 526
            ||:.||..|:.|.|..::..||:..|||:.:|.|:|||||.||.:|.|||||||||||||||:||
Zfish   417 EAKTKYTDYEFISDNSISWSASLHNRYTENSLRGVILDIHFLSQTDFLVCTFSSQVCRVAYEMMQ 481

  Fly   527 TMYPDAAHRFKSLDDIYYYGGQNAHNRRVVIAHKPRTHEDLQLRVGDLVSVAGNHWDGNSKGKNT 591
            |::|||:..|:|||||||:|||||||:..:..|:|||.||:.|..||::.||||||||||||.|.
Zfish   482 TLHPDASSFFRSLDDIYYFGGQNAHNQIAIYPHQPRTAEDIPLDPGDVIGVAGNHWDGNSKGINR 546

  Fly   592 RTNQGGLFPSFKVEEKVDTAKLPLY 616
            :..:.||:||:||:||::|.|.|.|
Zfish   547 KLGRTGLYPSYKVKEKIETVKYPTY 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FucT6	NP_572740.1	Fut8_like	223..545	CDD:211386	193/324 (60%)
FucT6	NP_572740.1	SH3_Fut8	552..606	CDD:212726	29/53 (55%)
fut8b	XP_005173879.1	Fut8_like	175..500	CDD:211386	193/324 (60%)
fut8b	XP_005173879.1	SH3_Fut8	507..561	CDD:212726	29/53 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574432
Domainoid	1	1.000	486	1.000	Domainoid score	I381
eggNOG	1	0.900	-	-		E1_KOG3705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	560	1.000	Inparanoid score	I1063
OMA	1	1.010	-	-		QHG48759
OrthoDB	1	1.010	-	-		D1290594at2759
OrthoFinder	1	1.000	-	-		FOG0006332
OrthoInspector	1	1.000	-	-		otm25851
orthoMCL	1	0.900	-	-		OOG6_105427
Panther	1	1.100	-	-	O	PTHR13132
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4607
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770