DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and DUN1

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_010182.1	Gene:	DUN1 / 851457	SGDID:	S000002259	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	308	Identity:	104/308 - (33%)
Similarity:	159/308 - (51%)	Gaps:	38/308 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQ 76
            :|.....|:.||...:.||.|..:.|:....|:||::.|.||.......:..:...:      |:
Yeast   189 NKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQF------RE 247

  Fly    77 EISILRQVMGHPYIIDLQDVF-----ESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQ 136
            |.:||.:|. ||.|::|.|.|     :|....:||.|....||||:.:.....|.:.:::.:.:|
Yeast   248 ETNILMRVQ-HPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQ 311

  Fly   137 IFEGVEYIHAKSIVHRDLKPENILL----------------DENH---NVKITDFGFAKQLQEGE 182
            :..|::|:|.::|:|||:|||||||                ||:.   .|||.|||.||...|.:
Yeast   312 LLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQ 376

  Fly   183 KLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLR-NIM 246
            ....|||||.|:|||.|.      ..||:.:||:|:.|||::..|.|.|||..:.....|: .|:
Yeast   377 FTNTLCGTPSYVAPEVLT------KKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQIL 435

  Fly   247 EGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQM 294
            :.||:|.||.|..|.:....||...||::|.:|..:.|.|.||:||.:
Yeast   436 QAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDI 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	101/296 (34%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	99/292 (34%)
DUN1	NP_010182.1	FHA	36..136	CDD:238017
DUN1	NP_010182.1	STKc_CAMK	199..479	CDD:270687	99/292 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910