DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and Dclk1

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_038959175.1	Gene:	Dclk1 / 83825	RGDID:	68437	Length:	756	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	107/300 - (35%)
Similarity:	164/300 - (54%)	Gaps:	37/300 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EEDDLLPDKDAAKGFY------AKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESG 63
            ||.|        :||.      .:|:....:|.|..:.|:.|||:.|.:|:|.|||     .:|.
  Rat   390 EESD--------EGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKII-----KKSK 441

  Fly    64 ETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEK 128
            .....||::   .|:||||:|. ||.|:.|.:..:....::||.||...|:|||.:||....:|:
  Rat   442 CRGKEHMIQ---NEVSILRRVK-HPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTER 502

  Fly   129 KTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL----DENHNVKITDFGFAKQLQEGEKLTNLCG 189
            ....::..:...::|:|:.:|||||:||||:|:    |.:.::|:.|||.| .:.:| .|..:||
  Rat   503 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA-TIVDG-PLYTVCG 565

  Fly   190 TPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHR--KQMVMLRNIMEGKYSF 252
            ||.|:|||.:      ...||..:|||||.|||.:.||.|.|||...  .|.|:...|:.|:..|
  Rat   566 TPTYVAPEII------AETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDF 624

  Fly   253 TSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFN 292
            .||.|.::|:..|:||...|:|:..||.:..:||.||:.|
  Rat   625 PSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVN 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	102/283 (36%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	101/273 (37%)
Dclk1	XP_038959175.1	DCX1_DCLK1	55..143	CDD:340660
		DCX2	182..265	CDD:340589
		STKc_DCKL1	399..666	CDD:271085	101/282 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010