Protein Alignment PhKgamma and Stk33

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001419557.1
• Gene: Stk33 / 690861
• RGDID: 1590972
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 131/415 - (31%)
• Similarity: 206/415 - (49%)
• Gaps: 76/415 - (18%)

  Fly    28 ILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIID 92
            |||:|....|....:||||.::|.|.::    .|...::...:||   :|::||:.|. |.:||.
  Rat   117 ILGQGSFGMVIEATDKETGAKWAIKKVN----KEKAGSSAVKLLE---REVNILKTVK-HQHIIH 173

  Fly    93 LQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPE 157
            |:.||||...::||.|||..|||.:.|......||.:||.|::.:...:.|:|:|.|||||||.|
  Rat   174 LEQVFESPQKMYLVMELCEDGELKEVLDQRGHFSESETRLIIQSLASAIAYLHSKDIVHRDLKLE 238

  Fly   158 NIL-----LDENH----NVKITDFGFAKQLQEGEK----LTNLCGTPGYLAPETLKCNMFEGSPG 209
            ||:     :|:|:    |:|::|||.|.| :.|.:    :...||||.|:|||.:..:      .
  Rat   239 NIMVKSSFIDDNNEMNLNIKVSDFGLAVQ-KHGSRSESMMQTTCGTPIYMAPEVINAH------D 296

  Fly   210 YSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVV 274
            |||:.|||:.||||:.||.|.|||....:..:...|.:|:..|..|.|..:|:..|..:::.:.|
  Rat   297 YSQQCDIWSIGVIMYILLCGEPPFLANSEEKLFELIRKGELQFQDPVWDSVSDSAKSALKQLMKV 361

  Fly   275 DPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQ-----PEA------------ 322
            ||:.|||.||:|.:.:     |.|:....|.|     ||...:::     ||:
  Rat   362 DPAHRITAKELLDNQW-----LTGNTLSSARP-----TNVLEMMKEWKNNPESDDDTKADKETEQ 416

  Fly   323 ---SSYRFGQLNSSCAGAPNYLYCAPQSSYSSNRMRDGA----LDDAGASAASATCHVM------ 374
               ...:..::...   |||..: :| |:.|.|:..|.|    .|....|.:.:|.:.:
  Rat   417 HTEEKLKHNKIEEK---APNVNH-SP-SAKSVNQPTDEAKKPDADSVDMSPSDSTSYKLISAEIK 476

  Fly   375 -SPSNASNSYATNTTANTS--NSAL 396
             .|..:|.|.:....|.|:  :|||
  Rat   477 AEPEKSSGSVSHVAVAKTTLKSSAL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	103/275 (37%)
Stk33	NP_001419557.1	Protein Kinases, catalytic domain	110..378	CDD:473864	103/280 (37%)