DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and mylka

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_009302720.1	Gene:	mylka / 569510	ZFINID:	ZDB-GENE-030131-8207	Length:	1857	Species:	Danio rerio

Alignment Length:	301	Identity:	101/301 - (33%)
Similarity:	147/301 - (48%)	Gaps:	30/301 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DEEDDLLPD-------KDA-AKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATT 60
            |:|.:.:||       .|. .|.|   |:.::.||.|...||.:.|||.|.|.:|.|.|...:..
Zfish  1402 DDESEKVPDYRNVTIKTDVKVKDF---YDVEDRLGTGKFGTVFKLIEKSTKKVWAGKFIKAYSAK 1463

  Fly    61 ESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFD-YLTSVVT 124
            |.         |..||||:|:.. :.||.::...|.||....:.:|.|:...||||| .:.....
Zfish  1464 EK---------ENVRQEIAIMND-LHHPKLVQCIDAFEGKTDIVMVLEMISGGELFDRIIDEDFE 1518

  Fly   125 LSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL--DENHNVKITDFGFAKQLQEGEKLTNL 187
            |:|::....|.||.:||.:||.|.|||.|||||||:.  .....:|:.|||.|::|:....|..|
Zfish  1519 LTEREVIKYMLQIVDGVNFIHKKGIVHLDLKPENIMCVNKTGSKIKLIDFGLARRLENAGSLKVL 1583

  Fly   188 CGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSF 252
            .|||.::|||.:.   :|   ..|...|:|:.|||.:.|:.|..||........|.|:....:.|
Zfish  1584 FGTPEFVAPEVIN---YE---AISYATDMWSIGVICYILVSGLSPFMGDNDNETLSNVTSATWDF 1642

  Fly   253 TSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQ 293
            ....:.:|||:.||.|...|..|...|:|..:..:||:..|
Zfish  1643 EDEAFDEISEEAKDFISNLLKKDMKARLTCDQCFQHPWLKQ 1683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	94/274 (34%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	93/270 (34%)
mylka	XP_009302720.1	I-set	85..175	CDD:254352
		Ig	91..165	CDD:299845
		I-set	212..300	CDD:254352
		Ig	231..301	CDD:299845
		PHA03255	283..>461	CDD:165513
		Ig	452..541	CDD:299845
		I-set	453..542	CDD:254352
		I-set	552..638	CDD:254352
		IGc2	565..628	CDD:197706
		I-set	661..750	CDD:254352
		Ig	678..747	CDD:143165
		I-set	759..848	CDD:254352
		Ig	762..846	CDD:299845
		I-set	1068..1157	CDD:254352
		Ig	1087..1152	CDD:143165
		Ig8_MLCK	1199..1296	CDD:143239
		I-set	1199..1288	CDD:254352
		FN3	1292..1381	CDD:238020
		STKc_MLCK1	1423..1681	CDD:271093	95/276 (34%)
		Pkinase	1426..1681	CDD:278497	93/270 (34%)
		I-set	1756..1846	CDD:254352
		IGc2	1769..1836	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010