DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PhKgamma and mylk3

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001099057.1	Gene:	mylk3 / 561635	ZFINID:	ZDB-GENE-030131-3497	Length:	715	Species:	Danio rerio

Alignment Length:	278	Identity:	95/278 - (34%)
Similarity:	138/278 - (49%)	Gaps:	19/278 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQV 84
            |....|.|:||.|....|.:|.|..:|...|||||.:....|..|         .:.||.::.|
Zfish   401 YYAVNPVEVLGGGRFGQVHKCAELSSGLTLAAKIIKVRGMKERDE---------VKNEIGVMNQ- 455

  Fly    85 MGHPYIIDLQDVFESDAFVFLVFELCPKGELFD-YLTSVVTLSEKKTRTIMRQIFEGVEYIHAKS 148
            :.|..:|.|.|.|||...:.|:.|....||||: .:.....|:|.......|||.|||:|:|.:.
Zfish   456 LNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQY 520

  Fly   149 IVHRDLKPENILL--DENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYS 211
            |:|.||||||||.  ...:.:||.|||.|::.:..|||....|||.:||||.:..: |...|
Zfish   521 ILHLDLKPENILCVNSTGNQIKIIDFGLARKYRPREKLKVNFGTPEFLAPEVVNYD-FVSFP--- 581

  Fly   212 QEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDP 276
              .|:|:.|||.:.||.|..||........:.||:..|:.|.:..:.::||:.||.|...||...
Zfish   582 --TDMWSVGVITYMLLSGLSPFMGDNDAETMNNILHAKWEFDTEAFENVSEEAKDFISSLLVSAK 644

  Fly   277 SQRITVKEVLRHPFFNQM 294
            ..|::....::|.:.|.:
Zfish   645 CSRLSASGCMKHSWLNNL 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	94/273 (34%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	93/270 (34%)
mylk3	NP_001099057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..114
		STKc_MLCK3	399..659	CDD:271094	94/273 (34%)
		S_TKc	407..659	CDD:214567	92/267 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.030