DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and pskh1

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001018546.1	Gene:	pskh1 / 554840	ZFINID:	ZDB-GENE-050119-1	Length:	422	Species:	Danio rerio

Alignment Length:	415	Identity:	121/415 - (29%)
Similarity:	194/415 - (46%)	Gaps:	94/415 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVM 85
            |||:.|.::|||..|.|.|...:.|.:.:|.|:|         ||......|....|:.:||:|.
Zfish    94 AKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMI---------ETRYREGREVCESELCVLRRVR 149

  Fly    86 GHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIV 150
             |..||.|.:|||:...|::|.||...|||||.:.:..:.:|:....:::.:.:||:|:|...|.
Zfish   150 -HTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGIT 213

  Fly   151 HRDLKPENILL---DENHNVKITDFGFAKQLQEGEK--LTNLCGTPGYLAPETLKCNMFEGSPGY 210
            ||||||||:|.   ..:..:.|||||.|...::|::  :...||||.|:|||.|.      ...|
Zfish   214 HRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILV------RKPY 272

  Fly   211 SQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVD 275
            :..||:||.|||.:.||.|..||....:|.:.|.|::|||||:...|..:|...||.|.:.|.||
Zfish   273 TNAVDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVD 337

  Fly   276 PSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQLNSSCAGAPNY 340
            |::|::..:.|:||:...|.              |.::.::|
Zfish   338 PNERLSAGQALKHPWIVSMA--------------ASSSMKNL----------------------- 365

  Fly   341 LYCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALASASSHKTL 405
                 ..|.|.|.::          .||:.||               :..:|.||.:|.|:..:.
Zfish   366 -----HRSISQNLLK----------RASSRCH---------------STKSSQSARSSRSTKSSK 400

  Fly   406 TAMVYYQQQPQQHQTQQQQQQYQQQ 430
            .      ::.::.:.::..::||||
Zfish   401 A------RRLREKELRELNRRYQQQ 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	102/274 (37%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	100/272 (37%)
pskh1	NP_001018546.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..80
		STKc_PSKH1	94..353	CDD:270989	102/274 (37%)
		S_TKc	96..353	CDD:214567	100/272 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	376..422		13/65 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920