DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and mylkb

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_009300538.1	Gene:	mylkb / 492576	ZFINID:	ZDB-GENE-041111-150	Length:	966	Species:	Danio rerio

Alignment Length:	303	Identity:	94/303 - (31%)
Similarity:	150/303 - (49%)	Gaps:	29/303 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKDEED------DLLPDKD-AAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGA 58
            ::.|:|:      |::..|| :.|.|   |:.::.||.|....|.:.:||.:.|.:|.|.|...:
Zfish   501 VSDDDEEKEPEYRDVVIKKDCSVKDF---YDIEDRLGTGKFGQVFKLVEKSSKKVWAGKFIKAFS 562

  Fly    59 TTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSV- 122
            ..|.         |..||||.|:.. :.||.::...|.||..:.:.:|.|:...||||:.:...
Zfish   563 QKEK---------ENVRQEIGIMNS-LHHPKLVQCMDAFEGKSDMVMVMEMISGGELFERIVDED 617

  Fly   123 VTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL--DENHNVKITDFGFAKQLQEGEKLT 185
            ..|:|::....|.||.:||::||.:.|||.|||||||:.  .....:|:.|||.|::|::...|.
Zfish   618 FELTEREVIKYMLQIIDGVQFIHKQGIVHLDLKPENIMCINKTGSKIKLIDFGLARRLEDSGSLK 682

  Fly   186 NLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKY 250
            .|.|||.::|||.:.   :|   ..|...|:|:.|||.:.|:.|..||........|.|:....:
Zfish   683 VLFGTPEFVAPEVIN---YE---AISYPTDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATW 741

  Fly   251 SFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQ 293
            .|....:.:||:..||.|.:.|..|...|:|..:...|.:..|
Zfish   742 DFEDEAFDEISDQAKDFISRLLKKDMRARLTCAQCFEHSWLKQ 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	87/274 (32%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	86/270 (32%)
mylkb	XP_009300538.1	I-set	166..255	CDD:254352
		IGc2	180..245	CDD:197706
		Ig	296..394	CDD:299845
		I-set	296..386	CDD:254352
		FN3	390..475	CDD:238020
		PKc_like	524..782	CDD:304357	88/276 (32%)
		Pkinase	527..782	CDD:278497	86/270 (32%)
		I-set	860..950	CDD:254352
		IGc2	873..940	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010