DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and Camk1d

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001100835.1	Gene:	Camk1d / 307124	RGDID:	1560691	Length:	385	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	136/423 - (32%)
Similarity:	194/423 - (45%)	Gaps:	69/423 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKDEEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGAT--TESG 63
            ||::..:.....|..|:.....:|.||.||.|..|.|....||.|||.||.|.|...|.  .||.
  Rat     1 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESS 65

  Fly    64 ETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEK 128
            ..|          ||::||::. |..|:.|:|::||...::||.:|...|||||.:......:||
  Rat    66 IEN----------EIAVLRKIK-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEK 119

  Fly   129 KTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL---DENHNVKITDFGFAKQLQEGEKLTNLCGT 190
            ...|::||:.:.|.|:|...||||||||||:|.   ||...:.|:|||.:|...:|:.::..|||
  Rat   120 DASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGT 184

  Fly   191 PGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSP 255
            |||:|||.|      ....||:.||.|:.|||.:.||.|.|||:......:...|::.:|.|.||
  Rat   185 PGYVAPEVL------AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSP 243

  Fly   256 EWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNS------ 314
            .|.|||:..||.||..:..||::|.|.::..|||:......:....|.:   ..||...
  Rat   244 YWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHES---VSAQIRKNFAKSK 305

  Fly   315 -----------RHLLQPEASSYRFGQLNSSCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAAS 368
                       ||:.:.:..|    .|:||.|...:.|..|.|..               ..|.|
  Rat   306 WRQAFNATAVVRHMRRLQLGS----SLDSSNASVSSNLSLASQKD---------------CLAPS 351

  Fly   369 ATCHVMSPSNASNSY--------ATNTTANTSN 393
            ..|..:|.|:.....        .|.||.:|.:
  Rat   352 TLCSFLSSSSGVAGVGAERRPRPTTVTTGHTGS 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	110/276 (40%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	110/272 (40%)
Camk1d	NP_001100835.1	STKc_CaMKI_delta	12..312	CDD:271070	115/319 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920