DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and Dclk3

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_766516.2	Gene:	Dclk3 / 245038	MGIID:	3039580	Length:	790	Species:	Mus musculus

Alignment Length:	278	Identity:	100/278 - (35%)
Similarity:	158/278 - (56%)	Gaps:	23/278 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGH 87
            |:...::|.|..:||:.|..:||.:.:|.|:||  .:...|:.      :....||.|: |.:.|
Mouse   514 YDIGGVIGDGNFATVKECRHRETKQAYAMKMID--KSQLKGKE------DIVDSEILII-QSLSH 569

  Fly    88 PYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHR 152
            |.|:.|.:|:|::|.::|:.|....|:|||.:...|...|.:...::..:.:.:.::|.|:||||
Mouse   570 PNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHR 634

  Fly   153 DLKPENILLDENHN----VKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQE 213
            |:||||:|:..|.:    :|:.|||.||.:.  ..:..:||||.|:|||.|      ...||..|
Mouse   635 DVKPENLLVQRNEDKSITLKLADFGLAKYVV--RPIFTVCGTPTYVAPEIL------SEKGYGLE 691

  Fly   214 VDIWACGVIMFTLLVGCPPFW--HRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDP 276
            ||:||.|||::.||.|.|||.  .|.|..:...|..|::.|.||.|.:||:..|||:|..|.|||
Mouse   692 VDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDP 756

  Fly   277 SQRITVKEVLRHPFFNQM 294
            .:|.|.::||:||:...:
Mouse   757 KKRYTAEQVLQHPWIEMV 774

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	100/273 (37%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	100/273 (37%)
Dclk3	NP_766516.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		UBQ	92..177	CDD:294102
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..290
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..506
		PKc_like	513..770	CDD:304357	99/272 (36%)
		S_TKc	514..771	CDD:214567	100/273 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920