Protein Alignment PhKgamma and chkr-2

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_508060.1
• Gene: chkr-2 / 191613
• WormBaseID: WBGene00011612
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 277
• Identity: 78/277 - (28%)
• Similarity: 130/277 - (46%)
• Gaps: 25/277 - (9%)

  Fly    22 KYE-PKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATR---QEISILR 82
            ||. ...:||:|....|....:|......|.|.::...:|.....     :..||   .|:.:::
 Worm   167 KYHVTSHLLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRA-----IAKTRDIQNEVEVMK 226

  Fly    83 QVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLT----SVVTLSEKKTRTIMRQIFEGVEY 143
            : :.||.|:.:.|......:.::|.|....||.|..|.    :.:.|.|...:....|:.:.|.|
 Worm   227 K-LSHPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAFQLIDAVLY 290

  Fly   144 IHAKSIVHRDLKPENILLD---ENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFE 205
            :|:..|.|||:||||||..   |...:|:||||.||  ....::...||||.|.|||.:.....|
 Worm   291 LHSVGICHRDIKPENILCSNKAERCILKLTDFGMAK--NSVNRMKTHCGTPSYCAPEIVANQGVE 353

  Fly   206 GSPGYSQEVDIWACGVIMFTLLVGCPPFWHR-KQMVMLRNIMEGKYSFTSPEWADISEDPKDLIR 269
                |:.:||||:.|.::|....|.|||... ..:.|...::.|:. |...:|..|:::.:::|:
 Worm   354 ----YTPKVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLTGRL-FFHEQWHRITDETQNMIQ 413

  Fly   270 KCLVVDPSQRITVKEVL 286
            ..|.|:|..|.:..|::
 Worm   414 WMLTVEPLIRPSAVELM 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	78/277 (28%)
chkr-2	NP_508060.1	FHA_CHK2	45..153	CDD:438718
		Protein Kinases, catalytic domain	161..435	CDD:473864	78/277 (28%)