Protein Alignment PhKgamma and Y50D7A.3

DIOPT Version :9

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001368037.1
• Gene: Y50D7A.3 / 190101
• WormBaseID: WBGene00021753
• Length: 426
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 187/548 - (34%)
• Similarity: 274/548 - (50%)
• Gaps: 158/548 - (28%)

  Fly     4 DEEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPY 68
            ||......::|  :||.|.||.||:||||::|||||||||.:|:.||.||:|: :|.:..|....
 Worm    14 DESQHYRHEED--QGFNAAYESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDI-STEKQSENEAK 75

  Fly    69 HMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTI 133
            .:||.|..|:.||||:.|||.||.:.|.:::.:|:|.|||:.|:|||||.|.|.||:|||:.|.:
 Worm    76 RLLEETISEVEILRQLSGHPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVLNSTVTVSEKRARRL 140

  Fly   134 MRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPET 198
            |:|:|:||||:||:.|||||||.||||..:...:.|:|||||.::..|:||.:||||||||||||
 Worm   141 MKQLFDGVEYMHARDIVHRDLKLENILCIDEERIVISDFGFATRIPRGKKLRDLCGTPGYLAPET 205

  Fly   199 LKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISED 263
            ::|..::.:.|||.|||.||.||||:|||.||.||:||||::|||.|.:||:.|.:.:||:|:.:
 Worm   206 IRCQWYDNAEGYSLEVDEWALGVIMYTLLAGCAPFYHRKQLMMLRLIQQGKFEFRNEQWANITAE 270

  Fly   264 PKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFG 328
            .|:||.:.|.||.::||:.||.|.|.:   |:          |||
 Worm   271 AKNLITQLLQVDATKRISSKECLAHEW---MI----------PIA-------------------- 302

  Fly   329 QLNSSCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSN 393
                                                                             
 Worm   303 ----------------------------------------------------------------- 302

  Fly   394 SALASASSHKTLTAMVYYQQQPQQHQTQQQQQQYQQQQTTQLP-VQLQLQHPLLQTGGDGKQSVY 457
                                              |||....:| |:::|
 Worm   303 ----------------------------------QQQAPQMVPVVEVEL---------------- 317

  Fly   458 APPTVQLRKQSRFNARKKFQFAILVIRAIIRIRRLRFTAEPLHVEEAIRDPYRVKVLRKVIDGCA 522
                  ::.|:...|||:|:.||:.:|...|:.:.::....:..:...:.|:|.:.:|...:...
 Worm   318 ------VKDQTSERARKRFKTAIIWVRFFQRLAKYKYLKTVIDRDVLRKRPFRDRDIRHEAESSM 376

  Fly   523 FRVYGHWVKKGEGQNRAALFENTPRTEL 550
            |.||||||.:|...:|..||.|.||.::
 Worm   377 FSVYGHWVNRGFYYSRDMLFANKPRPKI 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	147/271 (54%)
		S_TKc	23..291	CDD:214567	145/267 (54%)
Y50D7A.3	NP_001368037.1	STKc_PhKG	27..298	CDD:270995	147/274 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159120
Domainoid	1	1.000	312	1.000	Domainoid score	I714
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H47915
Inparanoid	1	1.050	371	1.000	Inparanoid score	I1226
Isobase	1	0.950	-	0	Normalized mean entropy	S1671
OMA	1	1.010	-	-		QHG48604
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0002585
OrthoInspector	1	1.000	-	-		oto18777
orthoMCL	1	0.900	-	-		OOG6_105085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	1	1.000	-	-		X1942
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.790