Protein Alignment PhKgamma and Phkg1

DIOPT Version :9

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_035209.1
• Gene: Phkg1 / 18682
• MGIID: 97579
• Length: 388
• Species: Mus musculus
• Alignment Length: 553
• Identity: 217/553 - (39%)
• Similarity: 282/553 - (50%)
• Gaps: 180/553 - (32%)

  Fly     7 DDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDL--GATTESGETNPYH 69
            ||.|||..:|:.||..||||||||||:||.|||||.|.|.:|:|.||||:  |.:..|.|..  .
Mouse     4 DDALPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQ--E 66

  Fly    70 MLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIM 134
            :.|||.:|:.||::|.|||.||.|:|.:|::.|.||||:|..:||||||||..|||:||:||.||
Mouse    67 LREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIM 131

  Fly   135 RQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETL 199
            |.:.|.:..:|..:||||||||||||||:|.|:|:|||||:.|||.||||..:||||.|||||.:
Mouse   132 RALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEII 196

  Fly   200 KCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDP 264
            :|:|.:|.|||.:|||:|:.||||:|||.|.|||||||||:|||.||:|||.|.||||.|.|:..
Mouse   197 QCSMDDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTV 261

  Fly   265 KDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQ 329
            |||:.:.|||.|..|.:.:|.|.||||.:.|:.
Mouse   262 KDLVSRFLVVQPQDRCSAEEALAHPFFQEYVVE-------------------------------- 294

  Fly   330 LNSSCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNS 394
                                                                             
Mouse   295 ----------------------------------------------------------------- 294

  Fly   395 ALASASSHKTLTAMVYYQQQPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPLLQTGGDGKQSVYAP 459
                                                         :::|
Mouse   295 ---------------------------------------------EVRH---------------- 298

  Fly   460 PTVQLRKQSRFNARKKFQFAILVIRAIIRI----RRLRFTAEPLHVEEAIRDPYRVKVLRKVIDG 520
                      |:.|.||:...|.:.|.::|    ||::    |:..|..|||||.::.||::||.
Mouse   299 ----------FSPRGKFKVICLTVLASVKIYYQYRRVK----PVTREIVIRDPYALRPLRRLIDA 349

  Fly   521 CAFRVYGHWVKKGEGQNRAALFENTPRTELHAL 553
            .|||:||||||||:.|||||||||||:..|.:|
Mouse   350 YAFRIYGHWVKKGQQQNRAALFENTPKAVLLSL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	163/273 (60%)
		S_TKc	23..291	CDD:214567	161/269 (60%)
Phkg1	NP_035209.1	PKc_like	16..291	CDD:328722	165/276 (60%)
		Calmodulin-binding (domain-N)	303..327		7/27 (26%)
		Calmodulin-binding (domain-C)	343..367		16/23 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	344	1.000	Domainoid score	I1052
eggNOG	1	0.900	-	-		E1_KOG0599
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	442	1.000	Inparanoid score	I1638
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48604
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0002585
OrthoInspector	1	1.000	-	-		otm42869
orthoMCL	1	0.900	-	-		OOG6_105085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	1	1.000	-	-		X1942
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.770