DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PhKgamma and zyg-8

DIOPT Version :9

Sequence 1:	NP_511129.3	Gene:	PhKgamma / 32120	FlyBaseID:	FBgn0011754	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_499571.2	Gene:	zyg-8 / 176639	WormBaseID:	WBGene00006993	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	114/382 - (29%)
Similarity:	182/382 - (47%)	Gaps:	55/382 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DEEDDLLPDKDAAK---GFYAKYEPKEILGRGISSTVRRCIEKETGKE-FAAKIIDLGATTESGE 64
            |....::||:|..:   ....|::...::|.|.::.|...|:|....: .|.|:|     .....
Worm   460 DRSGSVIPDQDQQRLPPLLDEKFQLVRLIGDGNTAVVYEVIDKTNNDDRKAMKVI-----ARENV 519

  Fly    65 TNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKK 129
            ....|::|   .|::||::: .|.:|:.|.|.:..|...:|..||...|:||::|..|..:.|:.
Worm   520 IGKEHLIE---MELAILQKI-DHTFIVQLYDHWFVDDSYYLSLELIEMGDLFEHLRIVRRVPERD 580

  Fly   130 TRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENH----NVKITDFGFAKQL-QEGEKLTNLCG 189
            ...:|..:.:.:||||...|||||:|.||:|:.::.    .||:.|||.|.:: ::...|:.:||
Worm   581 AVRMMTCLGQALEYIHELGIVHRDVKLENLLIVKDEFGELGVKLADFGLAAEMPKDFGVLSTICG 645

  Fly   190 TPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHR--KQMVMLRNIMEGKYSF 252
            ||.|:|||.|      ...||..:|||||.|||::.:|||.|||...  .:..:...||.|::||
Worm   646 TPTYVAPEVL------NKTGYGCKVDIWAAGVILYAILVGFPPFQSSDGSEQDLFSAIMSGEFSF 704

  Fly   253 TSPEWADISEDPKDLIRKCLV-VDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRH 316
            .||.|.|:|...:.|| .||: .||..|.:..|:|...:   ||.:||
Worm   705 PSPSWDDVSWSVRHLI-MCLIHTDPFHRYSAGELLNDEW---MVNLGD----------------- 748

  Fly   317 LLQPEAS--SYRFGQLNSSCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAASATC 371
             :.||..  ::||.|..........    .|...|:|.|.....|.::.|...|.:|
Worm   749 -VDPEYEEWAHRFVQSKMHVEEEQE----TPYEYYTSRRTSMDELSESAAVEFSYSC 800

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	93/280 (33%)
PhKgamma	NP_511129.3	S_TKc	23..291	CDD:214567	92/276 (33%)
zyg-8	NP_499571.2	DCX	206..298	CDD:214711
		DCX	335..423	CDD:214711
		STKc_DCKL	481..742	CDD:270997	93/276 (34%)
		S_TKc	482..743	CDD:214567	92/279 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920