Protein Alignment PhKgamma and Camk1g

DIOPT Version :10

• Sequence 1: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_878262.1
• Gene: Camk1g / 171358
• RGDID: 621800
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 154/542 - (28%)
• Similarity: 226/542 - (41%)
• Gaps: 147/542 - (27%)

  Fly     1 MAKDEEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGET 65
            |.:.||:|....|.........:...|:||.|..|.|....::.|||.||.|.|         :.
  Rat     1 MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCI---------KK 56

  Fly    66 NPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKT 130
            :|.....:...||::|:::. |..|:.|:|::||....:||.:|...|||||.:......:||..
  Rat    57 SPAFRDSSLENEIAVLKRIK-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDA 120

  Fly   131 RTIMRQIFEGVEYIHAKSIVHRDLKPENILL---DENHNVKITDFGFAKQLQEGEKLTNLCGTPG 192
            ..:::|:...|:|:|...||||||||||:|.   :||..:.|||||.:|..|.| .::..|||||
  Rat   121 SLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG-VMSTACGTPG 184

  Fly   193 YLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEW 257
            |:|||.|      ....||:.||.|:.|||.:.||.|.|||:...:..:...|.||.|.|.||.|
  Rat   185 YVAPEVL------AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFW 243

  Fly   258 ADISEDPKDLIRKCLVVDPSQRITVKEVLRHPF-------------------------------F 291
            .||||..||.|...|..||::|.|.::.||||:                               |
  Rat   244 DDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAF 308

  Fly   292 NQMVLMGDRR-------HPA--------PPIAPAQTNSRHLLQPEASSYRFGQLNSSCAGAPNYL 341
            |...::...|       .|:        ||::||         ||.|  |.|..:||...||
  Rat   309 NAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPA---------PEVS--RPGSHDSSITEAP--- 359

  Fly   342 YCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALASASSHKTLT 406
                                           ::.||....:.   |....|:|:..||...::|.
  Rat   360 -------------------------------ILDPSTPLPAL---TRLPCSHSSRPSAPGGRSLN 390

  Fly   407 AMVYYQQQPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPL-----------LQTGGDGKQSVYAPP 460
            .:|               ....:..::.:|:|   |.||           |..|..||.|..:.|
  Rat   391 CLV---------------NGSLRISSSLVPMQ---QGPLATGPCGCCSSCLNIGNKGKSSYCSEP 437

  Fly   461 TVQLRKQSRFNARKKFQFAILV 482
            |: .||.   |.::.|:..::|
  Rat   438 TL-FRKA---NKKQNFKSEVMV 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	106/305 (35%)
Camk1g	NP_878262.1	STKc_CaMKI_gamma	19..303	CDD:271068	106/300 (35%)
		Autoinhibitory domain	277..317		2/39 (5%)
		Calmodulin-binding	297..318		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..387		21/108 (19%)