DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bif and CG30389

DIOPT Version :9

Sequence 1:	NP_001259457.1	Gene:	bif / 32119	FlyBaseID:	FBgn0014133	Length:	1305	Species:	Drosophila melanogaster
Sequence 2:	NP_001261116.1	Gene:	CG30389 / 37410	FlyBaseID:	FBgn0050389	Length:	1037	Species:	Drosophila melanogaster

Alignment Length:	1063	Identity:	201/1063 - (18%)
Similarity:	329/1063 - (30%)	Gaps:	376/1063 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 KQRLQRSTSLNT-----LLDRDDDEVEVEEPEMTNSQVRAKSTPPPILGAKPTP----------- 420
            :||.||..:.:.     ||.:.....|..| |....|....||.....|:..||
  Fly   181 RQRKQREVAKDNEFYMQLLQQALPAEEAAE-EAAAGQAATSSTVVVANGSATTPALVASSGATAA 244

  Fly   421 --------KPSSQHQRPVSLGANGAGSAVNPPSNSDQAQTGAVANGGAGSGQRSRHFKRGNEVMK 477
                    :..:.|:...|.|| ||.|:.:..||.........::|.:||...|.....|
  Fly   245 NGVLATATQAQNHHEHHHSGGA-GASSSSSSNSNHHHHHHHNNSSGNSGSNHNSNSSSGG----- 303

  Fly   478 RARSVEALLCEKSPWNSQRISTAGAAAAAAPSPPAPKATAAAPSPVTSPTCVTIEDKIHNARERL 542
             |:.           ||...|.:||||::..:..|..|..||.:..:|
  Fly   304 -AKD-----------NSTSESASGAAASSITASSATGAALAAAASASS----------------- 339

  Fly   543 HSGTDTAPPKRLTSIIDDTERPPPDLVKQTLKMFEASANRRPRAAHRSNGVGGVASKVANYKSII 607
                                               ||......::..|.|
  Fly   340 -----------------------------------ASTTSGSSSSSASTG--------------- 354

  Fly   608 KDQKQPSSAAATPPPTGMGFASSTPLRHVHPDIIPRQVDSPVSALSVMMRRMELQEPETPERETR 672
               ||.||:||:...||....||||:             |..|||:..:...:.|....
  Fly   355 ---KQSSSSAASAATTGAATTSSTPV-------------SDFSALAASLATQQQQHQSV------ 397

  Fly   673 DAEATP-QSEALSETERNDRDEGDG------------------EVDDDNHNNN----DDDHDDGD 714
             |.|.| .|.|.|.:..::..:.||                  .:|.|.|.|.    |::|::|.
  Fly   398 -ATAYPATSSARSSSSTSEGVDADGCCGATSNGHAGGSRNHRRSMDKDKHRNKGDAADNEHNNGT 461

  Fly   715 DGSDNNEQRDKMGAAAAGDKPKPPAESAAGGAQRSFAASTENAHVASGSSSSTSASVRKLSNNND 779
            .....|...:::.:||                       |..|.|.:.||:|......| |:.:.
  Fly   462 RHGGKNSGNNQVDSAA-----------------------TATATVTATSSNSKDKDKEK-SDWDS 502

  Fly   780 SSSGPAVTKQIGVIRPLFNSQGAGSTPLTSREIEKNRINEMKKSTATDAGGSVSGSGTVAGAGSG 844
            |:|.|...:|.|..:   :.:.||:.      :.....|.::..||     ||..:..|..|..|
  Fly   503 STSYPQQQQQGGKEK---HEKKAGNA------VPNGNANHLEDETA-----SVEPTPPVEKATKG 553

  Fly   845 TSPTTSLDSVINTKEAASSETDASASPLWTLRKLRNQSQTAGG----GSGPSSSLHSTENTSMVF 905
            ....       ..|:.|:.:..:....|...:|.:::..||..    .|..|||..||.:.::..
  Fly   554 RRNR-------GKKDNAAKDNHSHQQQLAQQQKEKDKENTANNNNNDASSVSSSASSTSSNAIAN 611

  Fly   906 NFSKSTKEVPD---YIESDVVIYRRKRELPK--PNEPGFVLLGDLSVETSTDTDYDDYSMCPPSP 965
            ..||...::.:   .:|:||..||.:....|  .||....|..:|:.:::......:
  Fly   612 LASKVVSKICETCLKLEADVKKYRAEISHMKQIENELRQKLDANLTSKSTLQAKQKE-------- 668

  Fly   966 CD------VEFENA------NI-VIDGKSSIRQKPKESSFRVQFNDTLTSTFEYPSEASMTIEDP 1017
            ||      .|..||      |: .::.:.:..::.|:|         |.|......:|....|:.
  Fly   669 CDDLEKRIQELNNARHADMLNLQTVERRLNEERRQKQS---------LDSQLSNEKKARKLAEEK 724

  Fly  1018 PYADP--FGHVSKHHQMLLAEQMHLLQHQEQLE------------LEQMHQL------------- 1055
            . |.|  .....:..|.:..||..|....:|.|            :||.:::
  Fly   725 A-ARPECSSQCKQRRQQMDEEQKRLRSDLKQAEEAKQLAVEHGRKVEQEYRMLEAKLRNRESSQP 788

  Fly  1056 -------GLAPEQHHHVTVDEIIELPTSTAGHGHGIGLGHRSGAAGGGGTMLGNLPLD-YPSLGR 1112
                   .||..|..:.|:::.:...|                          .:.|| :.:||.
  Fly   789 DPEILLNALAAMQDKNATLEKNLSAET--------------------------RVKLDLFSALGA 827

  Fly  1113 GIILPQSPQQQSTQQQEQPEPAIATSATVAGLAVAMATEVEIE----------------PPL--- 1158
            .   .:..:.....::.:.:..|...|.:|.|...|...:.:.                |||
  Fly   828 A---KRQIEISDNHRRSKEDEVIDLKAKIAQLLAVMPDNLCMNTGPHGPSSSILRMNDTPPLQSG 889

  Fly  1159 PAPPVTVAKRPQLPAKPAQQQQQQAARRARPSVLLKPQYACFLQHDDDAPKSQPTAAGRPRKAAS 1223
            |.|     ..|.|....||:.||.            .|:....||.......|
  Fly   890 PGP-----SSPMLSLSAAQEYQQH------------QQHQQHQQHQQHQQHQQ------------ 925

  Fly  1224 FSLGNQRQSKEQQQHHHHYQPQHQQSKYERNDCSRSRGSCESPAPEHQQR------RRRPSLPSS 1282
               ..|.|.::.|||..|.|.||||...:.....:.:        :|||:      .::..:|.|
  Fly   926 ---HQQHQQQQHQQHQQHQQQQHQQQHQQHQQHQQHQ--------QHQQQGGGGPGSQQQMVPVS 979

  Fly  1283 ------LALSNASSALLQARIPG 1299
                  :|.:||::|...|...|
  Fly   980 VAAAFQVAAANAAAAANAAAANG 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bif	NP_001259457.1	None
CG30389	NP_001261116.1	Macoilin	2..893	CDD:286769	169/917 (18%)
		Ax_dynein_light	<624..711	CDD:287215	20/103 (19%)
		RILP-like	<696..803	CDD:304877	19/116 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458110
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13289
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030