DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptp10D and LOC569071

DIOPT Version :9

Sequence 1:	NP_996413.2	Gene:	Ptp10D / 32115	FlyBaseID:	FBgn0004370	Length:	1990	Species:	Drosophila melanogaster
Sequence 2:	XP_009295554.1	Gene:	LOC569071 / 569071	-ID:	-	Length:	457	Species:	Danio rerio

Alignment Length:	378	Identity:	146/378 - (38%)
Similarity:	205/378 - (54%)	Gaps:	30/378 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly  1161 LKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKR---- 1221
            |::...|:|...:|:||.:    :.:..|....|...:|..:.|...:::::...:..:.|
Zfish    70 LQAAQWYKVTATSFSGARR----SETISINCQTDPAGVIAGVLVFFLLVIIICAGVFVWIRYGSA 130

  Fly  1222 ----RRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHV 1282
                :|::....:|.|            |..|:.|....|.||:..||.|....||.|::||..|
Zfish   131 KFHNKRSHPPVESKVS------------ITHNKTIASDKFPEHFHNMSCDDKRNFSVEYKELGSV 183

  Fly  1283 GRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGH-NSPREFIVTQG 1346
            |..|....|.||.|:.|||.:.:||||.||..| .|:....|||.||||:||: |..|::|..||
Zfish   184 GVKQSSVTARLPENKDKNRISYVLPYDSSRVHL-TVNKAGDSDYFNANYIPGYGNVSRQYIAAQG 247

  Fly  1347 PLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWV 1411
            ||.||.:|||||.||..|.||||:|.|.|.|..||:||||.|..|..||::.|.:.:::....|.
Zfish   248 PLPSTVNDFWRMVWEQKSSAIVMVTNCTEDGMVKCEQYWPLDNTPCLYGNLLVAVKSENKSESWT 312

  Fly  1412 MTEFMLCR--GSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGA--EQRPIVVHCSAGV 1472
            :.||.:..  .|:.||:.|||||.|||.|||...:.|::|....|..|.:  ...|.||||||||
Zfish   313 LREFHVKNKMTSDTRIVHHFHFTAWPDHGVPCGTEDLIQFRELVRQHIESPFSAGPTVVHCSAGV 377

  Fly  1473 GRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLL 1525
            |::||.|.||.:|||:|....|.:...|..||..|..||:||.||:.:|||:|
Zfish   378 GQTGTLIALDVLLQQLNREKAVGVAAFVKEMRLSRPLMVETESQYVFLHQCIL 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp10D	NP_996413.2	fn3	124..205	CDD:278470
		fn3	220..304	CDD:278470
		fn3	315..391	CDD:278470
		FN3	405..494	CDD:238020
		FN3	511..574	CDD:238020
		FN3	583..671	CDD:238020
		fn3	683..753	CDD:278470
		fn3	787..850	CDD:278470
		fn3	866..935	CDD:278470
		fn3	961..1043	CDD:278470
		PTPc	1272..1525	CDD:214550	122/257 (47%)
		PTPc	1298..1525	CDD:238006	110/231 (48%)
LOC569071	XP_009295554.1	PTPc	173..431	CDD:214550	123/259 (47%)
LOC569071	XP_009295554.1	PTPc	199..431	CDD:238006	111/233 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16347at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920